Clinical trialNCT02814643CompletedPhase 3Interventional

Study to Evaluate the Potential Effect of Benralizumab on the Humoral Immune Response to the Seasonal Influenza Vaccination in Adolescent and Young Adult Patients With Severe Asthma

SponsorAstraZenecaEnrollment103Asthma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a randomized, double-blind, parallel group, placebo-controlled study designed to investigate the potential effect of a fixed dose of benralizumab administered subcutaneously (SC) on antibody responses following seasonal influenza virus vaccination

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Pamela L Zeitlin, M.D. Ph.D.
Johns Hopkins University
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

24 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Research Site
Birmingham, Alabama, United States
Research Site
Mesa, Arizona, United States
Research Site
Huntington Beach, California, United States
Research Site
Newport Beach, California, United States
Research Site
Aurora, Colorado, United States
Research Site
Colorado Springs, Colorado, United States
Research Site
Denver, Colorado, United States
Research Site
Aventura, Florida, United States
Research Site
Miami, Florida, United States
Research Site
Miami, Florida, United States
Research Site
Minneapolis, Minnesota, United States
Research Site
Bellevue, Nebraska, United States
Research Site
Northfield, New Jersey, United States
Research Site
Edmond, Oklahoma, United States
Research Site
Oklahoma City, Oklahoma, United States
Research Site
Medford, Oregon, United States
Research Site
North Charleston, South Carolina, United States
Research Site
Arlington, Texas, United States
Research Site
El Paso, Texas, United States
Research Site
New Braunfels, Texas, United States
Research Site
San Antonio, Texas, United States
Research Site
San Antonio, Texas, United States
Research Site
Waco, Texas, United States
Research Site
Clinton, Utah, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Benralizumab →Benralizumab PlaceboSeasonal influenza virus vaccine

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Jul 2016
Primary completion: 24 Jan 2017
Completion: 24 Jan 2017
Last update posted: 24 Oct 2018
Registered enrollment: 103
Registry id: NCT02814643

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.