Clinical trialNCT02910037CompletedInterventional

Precision Diagnosis of Acute Infectious Diseases; Neuroinflammatory Cohort

SponsorUniversity of California, San FranciscoEnrollment214EncephalitisMeningitis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study aims to use a clinically validated metagenomic next-generation sequencing (mNGS) assay to provide a demonstration of precision medicine for diagnosis of acute infectious disease in hospitalized patients. From June 2016 to June 2017, 200 patients will be enrolled from multiple hospitals in California and outside of California. Patients will be evaluated to determine the impact on the mNGS assay on diagnostic yield, hospital costs and clinical outcomes.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Charles Y Chiu, MD, PhD
University of California, San Francisco
Principal Investigator
clinicaltrials.gov ↗
Hannah Sample, BS
University of California, San Francisco
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California, Davis Medical Center
Davis, California, United States
Children'S Hospital Los Angeles
Los Angeles, California, United States
University of California, Los Angeles Medical Center
Los Angeles, California, United States
University of California, San Francisco Medical Center
San Francisco, California, United States
Children'S Hospital Colordao
Denver, Colorado, United States
Children'S National Medical Center
Washington D.C., District of Columbia, United States
St. Jude Children'S Research Hospital
Nashville, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Jun 2016
Primary completion: 31 Jul 2017
Completion: 31 Jul 2017
Last update posted: 27 May 2021
Registered enrollment: 214
Registry id: NCT02910037

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.