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Clinical trialNCT02932280Active, not recruitingPhase 1/PHASE2Interventional

Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

SponsorMemorial Sloan Kettering Cancer CenterEnrollment14Central Nervous System TumorLeukemiaLymphomaSolid Tumor
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to test the safety of neratinib at different dose levels and to find out what effects, good and bad, it has on the patients and the cancer.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Alberta Children'S Hospital

    Calgary, Alberta, Canada

United States
  • Phoenix Children'S Hospital

    Phoenix, Arizona, United States

  • Arkansas Children'S Hospital

    Little Rock, Arkansas, United States

  • Stanford University School of Medicine and Stanford Cancer Institute

    Palo Alto, California, United States

  • Arnold Palmer Hospital for Children

    Orlando, Florida, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • Pennsylvania State Hershey Children'S Hospital

    Hershey, Pennsylvania, United States

  • University of Texas

    San Antonio, Texas, United States

  • Huntsman Cancer Institue

    Salt Lake City, Utah, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Neratinib →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Oct 2016
Primary completion
31 Oct 2026
Completion
31 Oct 2026
Last update posted
5 Dec 2025
Registered enrollment
14
Registry id
NCT02932280
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.