Clinical trialNCT02946853CompletedInterventional

Junctional AV Ablation in CRT-D: JAVA-CRT

SponsorUniversity of RochesterEnrollment26Atrial Fibrillation (Permanent)Systolic Heart Failure

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Cardiac resynchronization therapy (CRT) is a demonstrably effective device intervention for patients with heart failure with reduced ejection fraction and specific indication. However, many patients with heart failure (HF) are unable to maintain sinus rhythm and approximately 30-36% of CRT patients are in atrial fibrillation (AF).

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jonathan S Steinberg, MD
University of Rochester
Principal InvestigatorKOL profile →
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

21 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Arkansas Cardiology
Little Rock, Arkansas, United States
Huntington Memorial Hospital
Pasadena, California, United States
Emory Healthcare
Atlanta, Georgia, United States
Saint Alphonsus Regional Medical Center
Boise, Idaho, United States
University of Iowa
Iowa City, Iowa, United States
Lahey Clinic
Burlington, Massachusetts, United States
University of Massachusetts-Worchester
Worcester, Massachusetts, United States
William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, United States
Catholic Medical Ctr/new England Heart-Vasc Inst
Manchester, New Hampshire, United States
Suny at Buffalo
Buffalo, New York, United States
Northwell Hospital
New York, New York, United States
University of Rochester Medical Center
Rochester, New York, United States
Oregon Health & Science University
Portland, Oregon, United States
Portland Va Medical Center
Portland, Oregon, United States
Abington Memorial Hospital
Abington, Pennsylvania, United States
Drexel University College of Medicine
Philadelphia, Pennsylvania, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
Inova
Woodbridge, Virginia, United States
Kootenai Heart Clinics, Llc
Spokane, Washington, United States
Multicare Institute for Research and Innovation
Tacoma, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Oct 2016
Primary completion: 31 Aug 2020
Completion: 31 Aug 2020
Last update posted: 25 Jan 2022
Registered enrollment: 26
Registry id: NCT02946853

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.