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Clinical trialNCT02991898TerminatedPhase 2Interventional

Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies

SponsorMasonic Cancer Center, University of MinnesotaEnrollment3Acute Lymphoblastic LeukemiaAcute Myelogenous LeukemiaBiphenotypic LeukemiaBurkitt LymphomaChronic Lymphocytic LeukemiaChronic Myelogenous Leukemia+12 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a single center pilot study of a non-myeloablative umbilical cord blood transplant for the treatment of a hematological malignancy with a single infusion of T regulatory (Treg) given shortly after UCB transplantation.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Claudio Brunstein, MD, PhD

    Masonic Cancer Center, University of Minnesota

    Principal Investigator
    clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Masonic Cancer Center at University of Minnesota

    Minneapolis, Minnesota, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Infusion of Treg
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
16 Feb 2017
Primary completion
20 Jun 2019
Completion
20 Jun 2019
Last update posted
29 Sept 2020
Registered enrollment
3
Registry id
NCT02991898
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.