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Clinical trialNCT02997969CompletedPhase 1Interventional

Safety and Immune Response to a Clade C DNA HIV Vaccine

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment132HIV Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate the safety and immune response to an HIV clade C DNA vaccine and to an MF59-adjuvanted clade C Env protein in healthy, HIV-uninfected adults.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

South Africa
  • Aurum Tembisa Crs

    Johannesburg, Gauteng, South Africa

  • Isipingo Crs

    Westville, KwaZulu-Natal, South Africa

  • Aurum Institute Klerksdorp Crs

    Klerksdorp, North West, South Africa

Tanzania
  • National Institute for Medical Research (nimr) - Mbeya Medical Research Center (mmrc) Network Crs

    Mbeya, Tanzania

Zambia
  • Matero Reference Clinic Crs

    Lusaka, Zambia

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

DNA-HIV-PT123 vaccinePlaceboPROTEIN
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
21 Jun 2016
Primary completion
11 Jul 2018
Completion
11 Jul 2018
Last update posted
21 Jun 2019
Registered enrollment
132
Registry id
NCT02997969
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.