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Clinical trialNCT03003299RecruitingInterventional

PARTNER 3 Trial - Aortic Valve-in-Valve

SponsorEdwards LifesciencesEnrollment125Aortic StenosisAortic Stenosis, Severe
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failing aortic bioprosthetic valve.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

51 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • St. Paul'S Hospital, Providence Health Care

    Vancouver, British Columbia, Canada

    Recruiting
United States
  • Banner University Medical Center

    Phoenix, Arizona, United States

    Recruiting
  • University of California Los Angeles

    Los Angeles, California, United States

    Recruiting
  • Sutter Medical Center

    Sacramento, California, United States

    Recruiting
  • Kaiser Permanente San Francisco

    San Francisco, California, United States

    Withdrawn
  • Stanford University Medical Center

    Stanford, California, United States

    Recruiting
  • Uc Health Northern Colorado/medical Center of the Rockies

    Loveland, Colorado, United States

    Recruiting
  • Hartford Hospital

    Hartford, Connecticut, United States

    Recruiting
  • Jfk Medical Center/ Atlantic Clinical Research Collaborative

    Atlantis, Florida, United States

    Withdrawn
  • University of Florida, Gainesville

    Gainesville, Florida, United States

    Withdrawn
  • Emory University Hospital

    Atlanta, Georgia, United States

    Recruiting
  • Northwestern University Hospital

    Chicago, Illinois, United States

    Recruiting
  • Rush University Medical Center

    Chicago, Illinois, United States

    Recruiting
  • Northshore University Healthsystem

    Evanston, Illinois, United States

    Withdrawn
  • Prairie Education and Research Cooperative

    Springfield, Illinois, United States

    Withdrawn
  • Ochsner Clinic Foundation

    New Orleans, Louisiana, United States

    Recruiting
  • Brigham and Women'S Hospital

    Boston, Massachusetts, United States

    Recruiting
  • Henry Ford Hospital

    Detroit, Michigan, United States

    Recruiting
  • William Beaumont Hospital

    Royal Oak, Michigan, United States

    Withdrawn
  • University of Minnesota Medical Center

    Minneapolis, Minnesota, United States

    Withdrawn
  • Mayo Clinic

    Rochester, Minnesota, United States

    Recruiting
  • Saint Luke'S Hospital of Kansas City Mid America

    Kansas City, Missouri, United States

    Withdrawn
  • Washington University/ Barnes-Jewish Hospital

    St Louis, Missouri, United States

    Recruiting
  • Nebraska Heart Institute

    Lincoln, Nebraska, United States

    Withdrawn
  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, United States

    Withdrawn
  • Newark Beth Israel

    Newark, New Jersey, United States

    Recruiting
  • University of Buffalo

    Buffalo, New York, United States

    Withdrawn
  • Winthrop University Hospital

    Mineola, New York, United States

    Recruiting
  • Columbia University Medical Center/ New York Presbyterian Hospital

    New York, New York, United States

    Recruiting
  • Cornell University

    New York, New York, United States

    Recruiting
  • New York University (nyu) Langone Medical Center

    New York, New York, United States

    Withdrawn
  • Carolina'S Health System

    Charlotte, North Carolina, United States

    Withdrawn
  • Nc Heart and Vascular (rex Hospital)

    Raleigh, North Carolina, United States

    Withdrawn
  • the Christ Hospital

    Cincinnati, Ohio, United States

    Recruiting
  • the Cleveland Clinic Foundation

    Cleveland, Ohio, United States

    Recruiting
  • Oklahoma Cardiovascular Research Group

    Oklahoma City, Oklahoma, United States

    Withdrawn
  • Providence Heart & Vascular Institute

    Portland, Oregon, United States

    Recruiting
  • University of Pennsylvania Hospital

    Philadelphia, Pennsylvania, United States

    Recruiting
  • Allegheny General Hospital

    Pittsburgh, Pennsylvania, United States

    Recruiting
  • Lankenau Medical Center

    Wynnewood, Pennsylvania, United States

    Recruiting
11 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
5 Jan 2017
Primary completion
31 Jan 2033
Completion
30 Apr 2038
Last update posted
10 May 2024
Registered enrollment
125
Registry id
NCT03003299

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.