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Clinical trialNCT03026777CompletedPhase 4Interventional

Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation

SponsorLouisiana State University Health Sciences Center in New OrleansEnrollment337Acute Respiratory FailureIntubation Complication
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Endotracheal intubation is common in the care of critically ill patients. Complications of airway management in this setting are frequently encountered and may be associated with an increased risk of death. The prevention of complications during urgent and emergent endotracheal intubation is a key focus for airway management research. Post-intubation hypotension (PIH), a common complication of endotracheal intubation in the critically ill, may be prevented by a bolus of intravenous fluid prior to the start of the procedure, but this approach has not been examined in a prospective trial. There are no randomized trials of intravenous fluid administration to prevent PIH in critically ill adults. The investigators propose a randomized trial of fluid loading to prevent PIH in critically ill adults.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Alabama Birmingham

    Birmingham, Alabama, United States

  • Ochsner Medical Center

    Jefferson, Louisiana, United States

  • Lsuhsc and University Medical Center

    New Orleans, Louisiana, United States

  • Lahey Medical Center

    Burlington, Massachusetts, United States

  • Lincoln Medical Center

    The Bronx, New York, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, United States

  • University of Washington

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Intravenous crystalloid fluid, 500 mL
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jan 2017
Primary completion
31 Jan 2018
Completion
31 Jan 2018
Last update posted
5 Jan 2021
Registered enrollment
337
Registry id
NCT03026777

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.