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Clinical trialNCT03038672Active, not recruitingPhase 2Interventional

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

SponsorNational Cancer Institute (NCI)Enrollment54ALK-Positive Large B-Cell LymphomaDiffuse Large B-Cell Lymphoma Activated B-Cell TypeDiffuse Large B-Cell Lymphoma Associated With Chronic InflammationDiffuse Large B-Cell Lymphoma Germinal Center B-Cell TypeDiffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedEBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified+29 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

33 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Mayo Clinic Hospital in Arizona

    Phoenix, Arizona, United States

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, United States

  • Moffitt Cancer Center

    Tampa, Florida, United States

  • Moffitt Cancer Center - Mckinley Campus

    Tampa, Florida, United States

  • Moffitt Cancer Center-International Plaza

    Tampa, Florida, United States

  • Northside Hospital

    Atlanta, Georgia, United States

  • Northwestern University

    Chicago, Illinois, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, United States

  • University of Kansas Clinical Research Center

    Fairway, Kansas, United States

  • Haysmed

    Hays, Kansas, United States

  • University of Kansas Cancer Center

    Kansas City, Kansas, United States

  • Lawrence Memorial Hospital

    Lawrence, Kansas, United States

  • the University of Kansas Cancer Center - Olathe

    Olathe, Kansas, United States

  • University of Kansas Cancer Center-Overland Park

    Overland Park, Kansas, United States

  • University of Kansas Hospital-Indian Creek Campus

    Overland Park, Kansas, United States

  • Mercy Hospital Pittsburg

    Pittsburg, Kansas, United States

  • Salina Regional Health Center

    Salina, Kansas, United States

  • University of Kansas Health System Saint Francis Campus

    Topeka, Kansas, United States

  • University of Kansas Hospital-Westwood Cancer Center

    Westwood, Kansas, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, United States

  • Siteman Cancer Center at Saint Peters Hospital

    City of Saint Peters, Missouri, United States

  • Siteman Cancer Center at West County Hospital

    Creve Coeur, Missouri, United States

  • University Health Truman Medical Center

    Kansas City, Missouri, United States

  • University of Kansas Cancer Center - North

    Kansas City, Missouri, United States

  • University of Kansas Cancer Center - Lee'S Summit

    Lee's Summit, Missouri, United States

  • University of Kansas Cancer Center at North Kansas City Hospital

    North Kansas City, Missouri, United States

  • Siteman Cancer Center-South County

    St Louis, Missouri, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Dartmouth Hitchcock Medical Center/dartmouth Cancer Center

    Lebanon, New Hampshire, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, United States

  • Laura and Isaac Perlmutter Cancer Center at Nyu Langone

    New York, New York, United States

  • Ut Southwestern/simmons Cancer Center-Dallas

    Dallas, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

NivolumabVarlilumab
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
21 Dec 2018
Primary completion
26 May 2023
Completion
24 Oct 2026
Last update posted
12 May 2026
Registered enrollment
54
Registry id
NCT03038672

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.