Clinical trialNCT03041207CompletedObservational

Decreasing Antibiotic Use in Infants With Suspected Ventilator-associated Infection

SponsorVirginia Commonwealth UniversityEnrollment555Microbial ColonizationNosocomial Infections in ChildrenVentilator Associated Pneumonia

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a prospective study with three specific aims: (1) To convene a consensus conference to develop a guideline for antibiotic use in infants (age \< 3 yrs) with suspected ventilator-associated infection; (2) To evaluate outcomes before and after implementation of the antibiotic guideline; (3) To evaluate changes in the tracheal microbiome over the course of mechanical ventilation

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Douglas F Willson, MD
Virginia Commonwealth University
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

23 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Centre Hospitalier Universitaire Sainte-Justine
Montreal, Quebec, Canada

United States

Banner University Medical Center
Tucson, Arizona, United States
Arkansas Children'S Hospital
Little Rock, Arkansas, United States
Children'S Hospital of Los Angeles
Los Angeles, California, United States
Children'S Hospital of Orange County
Orange, California, United States
Connecticut Children'S Medical Center
Hartford, Connecticut, United States
University of Miami Health System - Holtz Children'S Hospital
Miami, Florida, United States
Children'S Healthcare of Atlanta - Egleston Hospital
Atlanta, Georgia, United States
Ann & Robert H. Lurie Children'S Hospital of Chicago
Chicago, Illinois, United States
Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, United States
C.S. Mott Children'S Hospital
Ann Arbor, Michigan, United States
Helen Devos Children'S Hospital
Grand Rapids, Michigan, United States
St. Louis Children'S Hospital - Washington University
St Louis, Missouri, United States
Children'S Hospital of Buffalo
Buffalo, New York, United States
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
University Hospitals Rainbow Babies & Children'S Hospital
Cleveland, Ohio, United States
Nationwide Children'S Hospital
Columbus, Ohio, United States
Oregon Health and Science University
Portland, Oregon, United States
Penn State Children'S Hospital
Hershey, Pennsylvania, United States
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Children'S Hospital of Richmond at Vcu
Richmond, Virginia, United States
Seattle Children'S Hospital
Seattle, Washington, United States
Medical College of Wisconsin
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 Mar 2017
Primary completion: 30 Apr 2019
Completion: 30 Apr 2019
Last update posted: 17 Jul 2019
Registered enrollment: 555
Registry id: NCT03041207

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.