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Clinical trialNCT03092375CompletedPhase 3Interventional

Multi-Center, Randomized, Open-Label Study of G/P +/- RBV for NS5A + SOF Previously Treated GT1 HCV Subjects

SponsorUniversity of FloridaEnrollment177HCVHepatitis C
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The study will enroll well-compensated cirrhotic as well as non-cirrhotic subjects treatment experienced with an NS5a Inhibitor + sofosbuvir and will include patients who did not complete the prescribed duration due to adverse event or any reason other than for non/poor compliance. Subjects will be randomized to 12 or 16 weeks of treatment.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

31 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Stanford University

    Palo Alto, California, United States

  • University of California, San Francisco

    San Francisco, California, United States

  • Georgetown University Hospital

    Washington D.C., District of Columbia, United States

  • Medstar Health Research Institute

    Washington D.C., District of Columbia, United States

  • Uf Hepatology Research at Ctrb

    Gainesville, Florida, United States

  • Uf Health Jacksonville-Gastroenterology Emerson

    Jacksonville, Florida, United States

  • Schiff Center for Liver Diseases/university of Miami

    Miami, Florida, United States

  • Orlando Immunology Center

    Orlando, Florida, United States

  • Atlanta Gastro Associates

    Atlanta, Georgia, United States

  • Atlanta Medical Center

    Atlanta, Georgia, United States

  • Rush University Medical Center

    Chicago, Illinois, United States

  • the Johns Hopkins Hospital/john G. Bartlett Specialty Practice

    Baltimore, Maryland, United States

  • Digestive Disease Associates, Pa

    Catonsville, Maryland, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, United States

  • University of Michigan

    Ann Arbor, Michigan, United States

  • Univ. of Minnesota Health Clinics and Surgery Center, Inc.

    Minneapolis, Minnesota, United States

  • Southern Therapy and Advanced Research

    Jackson, Mississippi, United States

  • Northwell Health - Sandra Atlaas Bass Center for Liver Diseases

    Manhasset, New York, United States

  • Columbia University Medical Center

    New York, New York, United States

  • Nyu Langone Medical Center

    New York, New York, United States

  • Weill Cornell Medicine, Hepatology

    New York, New York, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, United States

  • Duke University Medical Center

    Durham, North Carolina, United States

  • the Ohio State University

    Columbus, Ohio, United States

  • Integris Baptist Medical Center

    Oklahoma City, Oklahoma, United States

  • University of Pennsylvania-Perelman Center for Advanced Medicine

    Philadelphia, Pennsylvania, United States

  • Medical University of South Carolina

    Charleston, South Carolina, United States

  • Bon Secours Liver Institute of Virginia

    Richmond, Virginia, United States

  • Virginia Commonwealth University

    Richmond, Virginia, United States

  • University of Washington

    Seattle, Washington, United States

  • Virginia Mason Medical Center

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
20 Apr 2017
Primary completion
28 Dec 2018
Completion
6 Feb 2020
Last update posted
26 Feb 2020
Registered enrollment
177
Registry id
NCT03092375

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.