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Clinical trialNCT03094169TerminatedPhase 1/PHASE2Interventional

AVID100 in Advanced Epithelial Carcinomas

SponsorFormation BiologicsEnrollment49Head and Neck Squamous Cell CarcinomaNon Small Cell Lung CancerSolid Tumor, AdultTriple Negative Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Approximately 90 male and female patients with documented solid tumor malignancies of epithelial origin that are locally advanced or metastatic, and either refractory to standard therapy or for whom no standard therapy is available, will be entered into this Phase 1a/2a, multicenter, open-label, dose-escalation, cohort study of AVID100. Phase 2a will include evaluation of patient with EGFR-overexpressing squamous histology non-small cell lung cancer, squamous cell carcinoma of the head and neck, and triple negative breast cancer
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Yale

    New Haven, Connecticut, United States

  • Start Midwest

    Grand Rapids, Michigan, United States

  • the Tisch Cancer Institute-Mt. Sinai

    New York, New York, United States

  • Fox Chase

    Philadelphia, Pennsylvania, United States

  • Texas Oncology Midtown

    Austin, Texas, United States

  • Texas Oncology-Baylor -Charles A. Sammons Cancer Center

    Dallas, Texas, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, United States

  • Texas Oncology Mcallen

    McAllen, Texas, United States

  • Texas Oncology Ne San Antonio

    San Antonio, Texas, United States

  • Texas Oncology Tyler

    Tyler, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AVID100 IV
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Feb 2017
Primary completion
28 Nov 2020
Completion
30 Jan 2021
Last update posted
11 Jun 2025
Registered enrollment
49
Registry id
NCT03094169
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.