Clinical trialNCT03102034CompletedPhase 1Interventional

Evaluating the Infectivity, Safety, and Immunogenicity of a Single Dose of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine (D46/NS2/N/ΔM2-2-HindIII) in RSV-Seronegative Infants 6 to 24 Months of Age

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment32Respiratory Syncytial Virus Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study was to evaluate the safety, infectivity, and immunogenicity of a single dose of a recombinant live-attenuated respiratory syncytial virus (RSV) vaccine in RSV-seronegative infants and children 6 to 24 months of age. This study was a companion study to CIR 313.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Elizabeth (Betsy) J. McFarland, MD
University of Colorado School of Medicine and Children's Hospital Colorado, Pediatric Infectious Diseases
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

David Geffen School of Medicine at Ucla Nichd Crs
Los Angeles, California, United States
Usc la Nichd Crs
Los Angeles, California, United States
Univ. of Colorado Denver Nichd Crs
Aurora, Colorado, United States
Emory University School of Medicine Nichd Crs
Atlanta, Georgia, United States
Lurie Children'S Hospital of Chicago (lch) Crs
Chicago, Illinois, United States
Rush Univ. Cook County Hosp. Chicago Nichd Crs
Chicago, Illinois, United States
Johns Hopkins University Center for Immunization Research
Baltimore, Maryland, United States
Suny Stony Brook Nichd Crs
Stony Brook, New York, United States
Jacobi Med. Ctr. Bronx Nichd Crs
The Bronx, New York, United States
St. Jude Children'S Research Hospital Crs
Memphis, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

D46/NS2/N/ΔM2-2-HindIIIPlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 6 Apr 2017
Primary completion: 25 May 2018
Completion: 25 May 2018
Last update posted: 8 Feb 2022
Registered enrollment: 32
Registry id: NCT03102034

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.