Clinical trialNCT03126786CompletedPhase 2Interventional

Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema

SponsorClearside Biomedical, Inc.Enrollment71Diabetic Macular Edema

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this trial is to evaluate the safety and efficacy of suprachoroidal CLS-TA used with intravitreal aflibercept in subjects with DME.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Thomas Ciulla, MD
Clearside Biomedical
Study DirectorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

29 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Retinal Consultants of Arizona and Retinal Research Institute
Phoenix, Arizona, United States
Retina Centers, Pc
Tucson, Arizona, United States
California Retina Consultants
Bakersfield, California, United States
Retina Vitreous Medical Group Clinical Research
Beverly Hills, California, United States
Northern California Retina Vitreous Associates Medical Group, Inc.
Mountain View, California, United States
Retina Institute of California
Palm Desert, California, United States
Retina Consultants San Diego
Poway, California, United States
Medeye Associates
Miami, Florida, United States
Retina Specialty Institute
Pensacola, Florida, United States
Sarasota Retina Institute
Sarasota, Florida, United States
Center for Retina and Macular Disease
Winter Haven, Florida, United States
Emory Eye Center
Augusta, Georgia, United States
Marietta Eye Clinic
Marietta, Georgia, United States
Midwest Eye Institute
Indianapolis, Indiana, United States
Retina and Vitrous Associates of Kentucky
Lexington, Kentucky, United States
the Johns Hopkins Wilmer Eye Institute
Baltimore, Maryland, United States
Cumberland Valley Retina Consultants
Hagerstown, Maryland, United States
Retina Associates of Nj
Teaneck, New Jersey, United States
Western Carolina Retinal Associates
Asheville, North Carolina, United States
Oregon Retina Institute
Medford, Oregon, United States
Black Hills Regional Eye Institute
Rapid City, South Dakota, United States
Retina Research Institute of Texas
Abilene, Texas, United States
Texas Retina Associates-Arlington
Arlington, Texas, United States
Austin Retina Associates
Austin, Texas, United States
Texas Retina Associates
Dallas, Texas, United States
Valley Retina Institute
McAllen, Texas, United States
Valley Retina Institute, P.A.
McAllen, Texas, United States
Medical Center Ophthalmology Associates
San Antonio, Texas, United States
Retina Consultants of Houston
The Woodlands, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

IVT afliberceptSC CLS-TASham SC

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 11 Jul 2017
Primary completion: 17 Apr 2018
Completion: 17 Apr 2018
Last update posted: 13 May 2021
Registered enrollment: 71
Registry id: NCT03126786

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.