Clinical trialNCT03129945CompletedInterventional

Comparison of Nifedipine Versus Indomethacin for Acute Preterm Labor

SponsorUniversity of California, IrvineEnrollment36Obstetric Labor, Premature

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this research study is to determine the best medication to stop preterm labor. Recent studies have identify nifedipine and indomethacin as the two medications that are most likely to delay delivery for 48 hours, decrease maternal side effects and decrease some complications related to preterm delivery to the neonate. Both of these medications are commonly used to stop pre-term labor, therefore it has become our institution's standard to use these two medications in the setting of preterm labor. There have been limited studies comparing these two medications directly. A total of 450 participants will be asked to participate across all study sites.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Aisling Murphy, MD
University of California, Los Angeles
Principal Investigator
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Deborah A Wing, MD
University of California, Irvine
Principal Investigator
clinicaltrials.gov ↗
Gladys (Sandy) Ramos, MD
University of California, San Diego
Principal Investigator
clinicaltrials.gov ↗
Mary Norton, MD
University of California, San Francisco
Principal Investigator
clinicaltrials.gov ↗
Veronique Tache, MD
University of California, Davis
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California, Los Angeles
Los Angeles, California, United States
University of California, Irvine
Orange, California, United States
University of California, Davis
Sacramento, California, United States
University of California, San Diego
San Diego, California, United States
University of California, San Francisco
San Francisco, California, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Indomethacin →Nifedipine →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 17 Jan 2017
Primary completion: 18 Apr 2019
Completion: 18 Apr 2019
Last update posted: 5 Nov 2021
Registered enrollment: 36
Registry id: NCT03129945

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.