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Clinical trialNCT03150914Active, not recruitingPhase 3Interventional

Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial

SponsorUniversity of CincinnatiEnrollment60LAMLymphangioleiomyomatosis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a study to determine if early, long-term low dose sirolimus is effective for preventing progression to more advanced stages.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Stanford University

    Palo Alto, California, United States

  • National Jewish Hospital

    Denver, Colorado, United States

  • Emory University

    Atlanta, Georgia, United States

  • Loyola University

    Chicago, Illinois, United States

  • Brigham and Woman'S Hospital

    Boston, Massachusetts, United States

  • University of Cincinnati

    Cincinnati, Ohio, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Swedish Health

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Jan 2018
Primary completion
30 Jun 2025
Completion
30 Jun 2025
Last update posted
24 Dec 2024
Registered enrollment
60
Registry id
NCT03150914

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.