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Clinical trialNCT03153319Active, not recruitingPhase 1/PHASE2Interventional

Study to Evaluate the Safety and Efficacy of Adalimumab in MPS I, II, and VI

SponsorLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterEnrollment14Mucopolysaccharidosis IMucopolysaccharidosis IIMucopolysaccharidosis VI
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Randomized, double-blind, placebo-controlled, parallel-group, single-center study followed by open-label phase, to evaluate the effects of adalimumab compared to placebo on the change from baseline in joint and skeletal disease in children and adults with mucopolysaccharidosis (MPS) I, II or VI.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Lynda Polgreen, MD

    The Lundquist Institute at Harbor-UCLA Medical Center

    Principal Investigator
    clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • the Lundquist Institute at Harbor-Ucla Medical Center

    Torrance, California, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Adalimumab Injection [Humira]Saline Solution for Injection
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
5 Jun 2017
Primary completion
31 Jan 2027
Completion
28 Feb 2027
Last update posted
2 Feb 2026
Registered enrollment
14
Registry id
NCT03153319
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.