Clinical trialNCT03161704CompletedObservational

Validation and Refinement of Noninvasive Diagnostic Biomarkers for Endometriosis, The ENDOmarker Protocol

SponsorYale UniversityEnrollment114Endometriosis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study involves the prospective collection of endometrial biopsy tissue, serum, plasma, whole blood for DNA extraction, and urine from women who will be diagnosed as having (or not having) endometriosis at the time of scheduled surgery. The investigators plan to enroll approximately 500 women to validate and optimize the use of genomic classifiers alone or in combination with serum markers (such as cytokines) as a non-surgical marker of disease.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Anne Steiner, MD MPH
University of North Carolina
Principal Investigator
clinicaltrials.gov ↗
Christos Coutifaris, MD PhD
University of Pennsylvania
Principal Investigator
clinicaltrials.gov ↗
Esther Eisenberg, MD MPH
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Study Director
clinicaltrials.gov ↗
Heping Zhang, PhD
Yale University
Principal Investigator
clinicaltrials.gov ↗
Karl Hansen, MD PhD
University of Oklahoma
Principal Investigator
clinicaltrials.gov ↗
Kurt Barnhart, MD MSCE
University of Pennsylvania
Principal Investigator
clinicaltrials.gov ↗
Marcelle Cedars, MD
University of California, San Francisco
Principal Investigator
clinicaltrials.gov ↗
Michael Diamond, MD
Augusta University
Principal Investigator
clinicaltrials.gov ↗
Nanette Santoro, MD
University of Colorado, Denver
Study Chair
clinicaltrials.gov ↗
Richard Legro, MD
Milton S. Hershey Medical Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Yale University
New Haven, Connecticut, United States
Augusta University
Augusta, Georgia, United States
Wayne State University
Southfield, Michigan, United States
Pennsylvania State University
Hershey, Pennsylvania, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 8 Jul 2016
Primary completion: 31 Aug 2019
Completion: 31 Dec 2019
Last update posted: 6 Jan 2020
Registered enrollment: 114
Registry id: NCT03161704

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.