Clinical trialNCT03209609CompletedInterventional

VEST Venous Graft External Support Pivotal Study

SponsorVascular Graft Solutions Ltd.Enrollment224Coronary Artery Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Prospective, multi-center, randomized, within-subject-controlled , trial, enrolling patients with multi vessel atherosclerotic coronary artery disease, scheduled to undergo SVG CABG with arterial grafting of IMA to LAD and two or more saphenous vein grafts. In each patient, one SVG bypass will be randomized to be supported by the VEST, while another will not be supported and serve as control. Thus, the full cohort will provide a basis for comparison between two sets of SVGs: A VEST supported set; and an unsupported set.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Daniel Goldstein, MD
Montefiore Medical Center
Principal Investigator
clinicaltrials.gov ↗
John Puskas, MD
Icahn School of Medicine at Mount Sinai
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

17 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

London Health Sciences Centre, University Hospital
London, Ontario, Canada
Institut de Cardiologie de Montréal
Montreal, Quebec, Canada
Institut Universitaire de Cardiologie Et de Pneumologie de Québec - Université Laval
Québec, Quebec, Canada

United States

University of Southern California
Los Angeles, California, United States
Lutheran Hospital of Indiana
Fort Wayne, Indiana, United States
University of Maryland Baltimore
Baltimore, Maryland, United States
Mayo Clinic
Rochester, Minnesota, United States
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States
Montefiore Medical Center
New York, New York, United States
Mount Sinai St Luke'S
New York, New York, United States
New York Presbyterian Hospital/columbia University Medical Center
New York, New York, United States
Duke University Medical Center
Durham, North Carolina, United States
Wakemed Health & Hospitals
Raleigh, North Carolina, United States
Cleveland Clinic
Cleveland, Ohio, United States
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Baylor Scott & White Research Institute, the Heart Hospital Baylor Plano
Plano, Texas, United States
University of Virginia
Charlottesville, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 9 Jan 2018
Primary completion: 29 Sept 2020
Completion: 25 Sept 2024
Last update posted: 6 Feb 2025
Registered enrollment: 224
Registry id: NCT03209609

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.