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Clinical trialNCT03227029CompletedPhase 1Interventional

Evaluating the Infectivity, Safety, and Immunogenicity of Recombinant Live-Attenuated RSV Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 in RSV-Seronegative Infants 6 to 24 Months of Age

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment65Respiratory Syncytial Virus Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study was to evaluate the infectivity, safety, and immunogenicity of the recombinant live-attenuated respiratory syncytial virus (RSV) vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 when delivered as nose drops to RSV-seronegative infants 6 to 24 months of age. This study was a companion study to Center for Immunization Research (CIR) 321.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of California, Uc San Diego Crs- Mother-Child-Adolescent Hiv Program

    La Jolla, California, United States

  • David Geffen School of Medicine at Ucla Nichd Crs

    Los Angeles, California, United States

  • Usc la Nichd Crs

    Los Angeles, California, United States

  • Univ. of Colorado Denver Nichd Crs

    Aurora, Colorado, United States

  • Lurie Children'S Hospital of Chicago (lch) Crs

    Chicago, Illinois, United States

  • Rush Univ. Cook County Hosp. Chicago Nichd Crs

    Chicago, Illinois, United States

  • Johns Hopkins University Center for Immunization Research

    Baltimore, Maryland, United States

  • Boston Medical Center Ped. Hiv Program Nichd Crs

    Boston, Massachusetts, United States

  • Suny Stony Brook Nichd Crs

    Stony Brook, New York, United States

  • Jacobi Med. Ctr. Bronx Nichd Crs

    The Bronx, New York, United States

  • St. Jude Children'S Research Hospital Crs

    Memphis, Tennessee, United States

  • Texas Children'S Hospital Crs

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboRSV 276RSV ΔNS2/Δ1313/I1314L
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
22 Sept 2017
Primary completion
19 Dec 2019
Completion
1 Oct 2020
Last update posted
22 Apr 2022
Registered enrollment
65
Registry id
NCT03227029

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.