Clinical trialNCT03242642RecruitingInterventional

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

SponsorMedtronic CardiovascularEnrollment1,056Mitral Valve Regurgitation

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

David Adams, MD
Icahn School of Medicine at Mount Sinai
Principal Investigator
clinicaltrials.gov ↗
Martin Leon, MD
New York Presbyterian Hospital/Columbia University Medical Center
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Michael Mack, MD
Baylor Scott & White Hospital
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

85 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Royal Columbian Hospital
New Westminster, British Columbia, Canada
Razi Khan, MDShahzad Karim, MD
Recruiting
Saint Paul'S Hospital
Vancouver, British Columbia, Canada
Anson Cheung, MDDavid Wood, MD
Recruiting
Saint Michael'S Hospital
Toronto, Ontario, Canada
Gianluigi Bisleri, MDNeil Fam, MD
Recruiting
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Andrew Czarnecki, MDGideon Cohen, MD
Recruiting
Glen Royal Victoria Hospital
Montreal, Quebec, Canada
Benoit de VarennesNicolo Piazza
Recruiting
Montreal Heart Insitute
Montreal, Quebec, Canada
Ralph Stephan von Bardeleben, MDWalid Ben Ali, MD
Recruiting

Denmark

Rigshospitalet
Copenhagen, Denmark
Withdrawn

United States

University of Alabama Birmingham (uab) Hospital
Birmingham, Alabama, United States
James Davies, MDMustafa Ahmed, MD
Recruiting
Abrazo Heart Hospital
Phoenix, Arizona, United States
Merick Kirshner, MDTimothy Byrne, MD
Recruiting
Scripps Memorial Hospital
La Jolla, California, United States
Matthew Price, MDScott Brewster, MD
Recruiting
Cedars Sinai Medical Center
Los Angeles, California, United States
Raj Makkar, MDWen Cheng, MD
Recruiting
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States
Dhaval Trivedi, MDSomjot Brar, MD
Recruiting
Keck Hospital of the University of Southern California, Usc
Los Angeles, California, United States
Ray Vern Matthews, MDVaughn Starnes, MD
Recruiting
Pih Health Good Samaritan Hospital
Los Angeles, California, United States
Ali GheissariSteven Burstein
Recruiting
El Camino Hospital
Mountain View, California, United States
Chad Rammohan, MDVincent Gaudiani, MD
Recruiting
Kaiser Permanente San Francisco Medical Center
San Francisco, California, United States
Ahmad Sheikh, MDAndrew Rassi, MD
Recruiting
Stanford Hospital and Clinics
Stanford, California, United States
David Lee, MDJack Boyd, MD
Recruiting
Los Robles Regional Medical Center
Thousand Oaks, California, United States
Gregory Fontana, NDSaibal Kar, MD
Recruiting
Hartford Hospital
Hartford, Connecticut, United States
Robert HagbergSabet HashimTalhat Azemi, MD
Recruiting
Yale New Haven Hospital
New Haven, Connecticut, United States
John Forrest, MDPrashanth Vallabhajosyula, MD
Recruiting
Medstar Washington Hospital Center
Washington D.C., District of Columbia, United States
Christian Shults, MDRon Waksman, MD
Recruiting
Jfk Medical Center
Atlantis, Florida, United States
Cristiano Faber, MDMark Rothenberg, MD
Recruiting
Morton Plant
Clearwater, Florida, United States
Joshua J Rovin, MDLang L Lin, MD
Recruiting
Healthpark Medical Center
Fort Myers, Florida, United States
Daniel O'Hair, MDMurali Muppala, MD
Recruiting
North Florida Regional Medical Center
Gainesville, Florida, United States
Charles Klodell, MDIlie Barb, MD
Recruiting
Baptist Medical Center Jacksonville
Jacksonville, Florida, United States
Nathan Bates, MDRuby Satpahy, MD
Recruiting
University of South Florida Health
Tampa, Florida, United States
Hiram Bezerra, MDLucian Lozonschi, MD
Recruiting
Emory University
Atlanta, Georgia, United States
Adam Greenbaum, MDGaetano Paone, MD
Recruiting
Piedmont Atlanta Hospital
Atlanta, Georgia, United States
Pradeep Yadav, MDThourani Vinod, MD
Recruiting
Northwestern Memorial Hospital
Chicago, Illinois, United States
Charles Davidson, MDS. Chris Malaisrie, MD
Recruiting
Rush University Medical Center
Chicago, Illinois, United States
Antone Tatooles, MDHussam Suradi, MD
Recruiting
Mercyone Des Moines Medical Center
Des Moines, Iowa, United States
Atul Chawla, MDBart Jenson, MD
Recruiting
University of Kansas Medical Center
Kansas City, Kansas, United States
Emmanuel Daon, MDMark Wiley, MD
Recruiting
the Johns Hopkins Hospital
Baltimore, Maryland, United States
Hamza Aziz, MDRani Hasan, MD
Recruiting
University of Maryland Medical Center
Baltimore, Maryland, United States
Completed
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
David Liu, MDRoger Laham, MD
Recruiting
Brigham and Women'S Hospital
Boston, Massachusetts, United States
Ashraf Sabe, MDPinak Bipin Shah, MD
Recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
Ignacio Inglessis, MDSerguei Melnitchouk, MD
Recruiting
University of Michigan Health System
Ann Arbor, Michigan, United States
Stanley Chetcuti, MDSteven Bolling, MD
Recruiting
Henry Ford Saint John Hospital
Detroit, Michigan, United States
Sanjay Batra, MDTheodore Schreiber, MD
Recruiting

45 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 23 Oct 2017
Primary completion: 30 May 2027
Completion: 30 Sept 2036
Last update posted: 5 Aug 2026
Registered enrollment: 1,056
Registry id: NCT03242642

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.