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Clinical trialNCT03252353UnknownPhase 3Interventional

Efficacy and Safety of Octreotide Capsules (MYCAPSSA) in Acromegaly

SponsorChiasma, Inc.Enrollment56Acromegaly
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Octreotide capsule is a novel, orally-administered formulation of the commercially-available injectable drug octreotide. In a recent phase 3 trial, oral octreotide capsules demonstrated maintenance of biochemical response up to 13 months in the majority of patients with acromegaly previously managed with somatostatin analog injections (reference below).

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

60 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • St Vincent'S Private Hospital-Nsw

    Darlinghurst, New South Wales, Australia

  • Royal North Shore Public Hospital

    St Leonards, New South Wales, Australia

  • St Vincent'S Hospital-Vic

    Fitzroy, Victoria, Australia

  • the Alfred

    Melbourne, Victoria, Australia

  • Melbourne Health

    Parkville, Victoria, Australia

  • Keogh Institute (sir Charles Gardner)

    Nedlands, Western Australia, Australia

Bulgaria
  • University Specialized Hospital for Active Treatment of Endocrinology "acad. Iv. Pencev" Ead

    Sofia, Bulgaria

Canada
  • University of British Columbia

    Vancouver, British Columbia, Canada

  • St Joseph'S Health Care

    London, Ontario, Canada

  • Mcgill University Health Centre

    Montreal, Quebec, Canada

Denmark
  • Aarhus University Hospital

    Aarhus, Denmark

  • Rigshospitalet the Department of Endocrinology

    Copenhagen, Denmark

Germany
  • Rwth Aachen University Hospital, Medical Clinic Iii Division of Endocrinology and Diabetes

    Aachen, Germany

  • Klinikum Der Lmu Muenchen, Medizinische Klinik Und Poliklinik Iv, Endokrinologie

    Munich, Germany

Hungary
  • Magyar Honvedseg Egeszsegugyi Kozpont, Ii. Sz. Belgyogyaszati Osztaly

    Budapest, Hungary

  • University of Semmelweiss, Budapest

    Budapest, Hungary

  • Szegedi Tudományegyetem, I. Belgyógyászati Klinika

    Szeged, Hungary

Israel
  • Hadassah Ein-Karem Medical Center

    Jerusalem, Israel

  • Rabin Medical Center, Beilinson Hospital

    Petah Tikva, Israel

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, Israel

Italy
  • Policlinico Di Monserrato U.O.C. Endocrinologia E Diabetologia

    Monserrato, Italy

  • Azienda Ospedaliero-Universitaria Pisana, Università Di Pisa

    Pisa, Italy

Latvia
  • Riga Eastern Clinical University, Hospital Gailezers Department of Endocrinology

    Riga, Latvia

Netherlands
  • Leids Universitair Medisch Centrum

    Leiden, Netherlands

  • Erasmus Medisch Centrum

    Rotterdam, Netherlands

New Zealand
  • Dunedin Hospital

    Dunedin, New Zealand

  • Wellington Hospital

    Wellington, New Zealand

Poland
  • Katedra I Klinika Endokrynologii I Chorob Wewnetrznych

    Gdansk, Poland

  • Uniwersyteckie Centrum Okulistyki I Onkologii Samodzielny Publiczny Szpital Kliniczny Slaskiego Uniwersytetu Medycznego W Katowicach, Oddzial Endokrynologii

    Katowice, Poland

  • Szpital Uniwersytecki W Krakowie, Oddzial Kliniczny Endokrynologii

    Krakow, Poland

  • Klinika Chorob Wewnetrznych I Endokrynologii

    Warsaw, Poland

  • Samodzielny Publiczny Szpital Kliniczny Nr 1 We Wroclawiu, Klinika Endokrynologii, Diabetologii I Leczenia Izotopami

    Wroclaw, Poland

Slovenia
  • Medical University Centre Ljubljana

    Ljubljana, Slovenia

Sweden
  • Sahlgrenska University Hospital

    Gothenburg, Sweden

Turkey (Türkiye)
  • Ankara University, Faculty of Medicine

    Ankara, Turkey (Türkiye)

  • Hacettepe University Medical School

    Ankara, Turkey (Türkiye)

  • Ege University Medical Faculty Internal Diseases

    Izmir, Turkey (Türkiye)

  • Erciyes University Medical Faculty

    Kayseri, Turkey (Türkiye)

United Kingdom
  • University Hospitals Birmingham Nhs Foundation Trust, Queen Elizabeth Hospital

    Birmingham, United Kingdom

  • Central Manchester University Hospitals Nhs Foundation Trust, Manchester Royal Infirmary

    Manchester, United Kingdom

20 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Matching placeboOctreotide →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Sept 2017
Primary completion
13 Jun 2019
Completion
31 May 2022
Last update posted
23 Nov 2020
Registered enrollment
56
Registry id
NCT03252353

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.