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Clinical trialNCT03284710CompletedPhase 1/PHASE2Interventional

Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment132HIV Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate the safety and immune response to an HIV clade C vaccine and to an MF59- or alum-adjuvanted clade C Env protein in healthy, HIV-uninfected adults.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Mozambique
  • Polana Canico Health Research and Training Center (cispoc), National Institute of Health (ins) Crs

    Maputo, Mozambique

South Africa
  • Aurum Tembisa Crs

    Johannesburg, Gauteng, South Africa

  • Soweto Hvtn Crs

    Johannesburg, Gauteng, South Africa

  • Ethekwini Crs

    Durban, KwaZulu-Natal, South Africa

  • Emavundleni Crs

    Cape Town, Western Cape, South Africa

Zimbabwe
  • Seke South Crs

    Chitungwiza, Mashonaland East Province, Zimbabwe

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

ALVAC-HIVBivalent Subtype C gp120Bivalent Subtype C gp120 admixed with Al3 SuspensionBivalent Subtype C gp120/MF59
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
19 Jun 2017
Primary completion
12 Dec 2019
Completion
12 Dec 2019
Last update posted
24 Jul 2026
Registered enrollment
132
Registry id
NCT03284710
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.