FindMyKOL
Clinical trialNCT03322566CompletedPhase 2Interventional

A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06)

SponsorIncyte CorporationEnrollment233Lung Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study was to evaluate the efficacy and safety of pembrolizumab plus epacadostat with platinum-based chemotherapy versus pembrolizumab plus platinum-based chemotherapy plus placebo as first-line therapy in participants with metastatic non-small cell lung cancer (NSCLC).

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

94 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Blacktown Hospital

    Blacktown, New South Wales, Australia

  • Chris Obrien Lifehouse

    Camperdown, New South Wales, Australia

  • the Crown Princess Mary Cancer Centre Westmead

    Westmead, New South Wales, Australia

  • Southern Medical Day Care Centre

    Wollongong, New South Wales, Australia

  • Mncci Port Macquarie Base Hospital

    Port Macquarie, New South Wales (Australia), Australia

  • Cairns Base Hospital

    Cairns, Queensland, Australia

Canada
  • Bcca-Cancer Centre of the Southern Interior

    Kelowna, British Columbia, Canada

  • Lions Gate Hospital

    North Vancouver, British Columbia, Canada

  • Cisss de la Monteregie-Centre

    Greenfield Park, Quebec, Canada

  • Csss de Laval- Hopital de la Cite de la Sante

    Laval, Quebec, Canada

  • Ciusss Ouest de L'Ile - St-Mary'S Hospital

    Montreal, Quebec, Canada

  • Ciusss Du Nord-de-L'Ile-de-Montreal Hopital Du Sacre-Coeur de Montreal

    Montreal, Quebec, Canada

  • Chu de Quebec - Hotel-Dieu de Quebec

    Québec, Quebec, Canada

  • Ciusss de la Mauricie-Et-Du-Centre-Du-Quebec

    Trois-Rivières, Quebec, Canada

Hungary
  • Zala Megyei Korhaz Pozvai Telephely

    Pózva, Zalaegerszeg, Hungary

  • Orszagos Koranyi Tbc Es Pulmonologiai Intezet

    Budapest, Hungary

  • Veszprem Megyei Tudogyogyintezet

    Farkasgyepű, Hungary

  • Bekes Megyei Pandy Kalman Korhaz

    Gyula, Hungary

  • Cru Hungary Kft.

    Miskolc, Hungary

  • Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet

    Szolnok, Hungary

Ireland
  • St Vincents University Hospital

    Dublin, Ireland

Israel
  • Ha Emek Medical Center

    Afula, Israel

  • Soroka Medical Center

    Beersheba, Israel

  • Rambam Medical Center

    Haifa, Israel

  • Meir Medical Center

    Kfar Saba, Israel

  • Rabin Medical Center

    Petah Tikva, Israel

  • Chaim Sheba Medcal Center

    Ramat Gan, Israel

Italy
  • Centro Di Riferimento Oncologico

    Aviano, Italy

  • A.O.U. Policlinico Vittorio Emanuele - Presidio Gaspare Rodolico

    Catania, Italy

  • Fondazione Irccs Istituto Nazionale Dei Tumori

    Milan, Italy

  • Istituto Europeo Di Oncologia

    Milan, Italy

  • Ospedale San Gerardo - Asst Monza

    Monza, Italy

Mexico
  • Medical Care Research S.A. de C.V.

    Mérida, Yucatán, Mexico

  • Oaxaca Site Management Organization S.C.

    Oaxaca City, Mexico

  • Faicic Clinical Research

    Veracruz, Mexico

Russia
  • Belgorod Regional Oncology Dispensary

    Belgorod, Russia

  • Udmurtia Republic Regional Clinical Oncology Dispensary

    Izhevsk, Russia

  • Republican Clinical Oncology Dispensary of Tatarstan Moh

    Kazan', Russia

  • Central Clinical Hospital With Polyclinic

    Moscow, Russia

  • Moscow Research Oncology Institute

    Moscow, Russia

54 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

EpacadostatPembrolizumab →PlaceboPlatinum-Based Chemotherapy
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
9 Jan 2018
Primary completion
13 Dec 2018
Completion
16 Oct 2020
Last update posted
24 Jan 2022
Registered enrollment
233
Registry id
NCT03322566

Cross-registrations

EU-CTR / CTIS (EudraCT)2017-001810-27

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.