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Clinical trialNCT03387150CompletedPhase 1Interventional

Evaluating the Safety and Serum Concentrations of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered in Multiple Doses and Routes to Healthy, HIV-uninfected Adults

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment124HIV Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate the safety, tolerability, and serum concentrations of a human monoclonal antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), administered in multiple doses and routes to healthy, HIV-uninfected adults.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Switzerland
  • Lausanne Vaccine and Immunotherapy Center Crs

    Lausanne, Canton of Vaud, Switzerland

United States
  • Alabama Crs

    Birmingham, Alabama, United States

  • the Ponce de Leon Center Crs

    Atlanta, Georgia, United States

  • Brigham and Women'S Hospital Vaccine Crs (bwh Vcrs)

    Boston, Massachusetts, United States

  • Fenway Health (fh) Crs

    Boston, Massachusetts, United States

  • Columbia P&s Crs

    New York, New York, United States

  • Chapel Hill Crs

    Chapel Hill, North Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboVRC07-523LS
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
28 Feb 2018
Primary completion
7 Dec 2020
Completion
7 Dec 2020
Last update posted
5 Apr 2023
Registered enrollment
124
Registry id
NCT03387150

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.