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Clinical trialNCT03389802Active, not recruitingPhase 1Interventional

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

SponsorPediatric Brain Tumor ConsortiumEnrollment32CNS Primary Tumor, Not Otherwise Specified (NOS)Diffuse Intrinsic Pontine Gliomas (DIPG)Ependymoma, Not Otherwise Specified (NOS)Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)Medulloblastoma
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Children'S Hospital Los Angeles

    Los Angeles, California, United States

  • Lucile Packard Children Hospital Stanford University

    Palo Alto, California, United States

  • Children'S Hospital Colorado

    Aurora, Colorado, United States

  • Childrens National Medical Center

    Washington D.C., District of Columbia, United States

  • Children'S Healthcare of Atlanta

    Atlanta, Georgia, United States

  • Lurie Childrens Hospital-Chicago

    Chicago, Illinois, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • Cincinnati Children Hospital Medical Center

    Cincinnati, Ohio, United States

  • Children Hospital of Pittsburgh of Upmc

    Pittsburgh, Pennsylvania, United States

  • St. Jude Children Research Hospital

    Memphis, Tennessee, United States

  • Baylor College of Medicine

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Mar 2018
Primary completion
30 Sept 2023
Completion
30 Jun 2026
Last update posted
24 Jun 2026
Registered enrollment
32
Registry id
NCT03389802

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.