Clinical trialNCT03418961RecruitingPhase 3Interventional

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

SponsorSWOG Cancer Research NetworkEnrollment491CardiotoxicityHER2/Neu PositiveMetastatic Malignant Neoplasm in the BrainRecurrent Breast CarcinomaStage IV Breast Cancer AJCC v6 and v7

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Justin Floyd
SWOG Cancer Research Network
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

590 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

Advance Oncology Center
Aguadilla, Puerto Rico
Active, not recruiting
Doctor'S Cancer Center-Arecibo
Arecibo, Puerto Rico
Active, not recruiting
Cancer Center-Metro Medical Center Bayamon
Bayamón, Puerto Rico
Active, not recruiting
Hematologia Oncologia San Pablo
Bayamón, Puerto Rico
Active, not recruiting
Hima San Pablo Oncologic Hospital
Caguas, Puerto Rico
Active, not recruiting
Doctors Cancer Center
Manati, Puerto Rico
Active, not recruiting
Instituto Oncologia Moderna Ponce
Ponce, Puerto Rico
Active, not recruiting
Primary Care Physician Group
San Juan, Puerto Rico
Active, not recruiting
San Juan City Hospital
San Juan, Puerto Rico
Active, not recruiting
San Juan Community Oncology Group
San Juan, Puerto Rico
Active, not recruiting
Centro de Hematologia Y Oncologia del Sur
Santa Isabel, Puerto Rico
Active, not recruiting

Saudi Arabia

King Faisal Specialist Hospital and Research Centre
Riyadh, Saudi Arabia
Active, not recruiting

South Korea

National Cancer Center-Korea
Goyang-si, Gyeonggi-do, South Korea
Keun Seok Lee
Recruiting

United States

Alaska Breast Care and Surgery Llc
Anchorage, Alaska, United States
Suspended
Alaska Oncology and Hematology Llc
Anchorage, Alaska, United States
Suspended
Alaska Women'S Cancer Care
Anchorage, Alaska, United States
Suspended
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, United States
Suspended
Anchorage Oncology Centre
Anchorage, Alaska, United States
Suspended
Katmai Oncology Group
Anchorage, Alaska, United States
Suspended
Providence Alaska Medical Center
Anchorage, Alaska, United States
Suspended
Fairbanks Memorial Hospital
Fairbanks, Alaska, United States
Suspended
Chi Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas, United States
Suspended
Kaiser Permanente-Deer Valley Medical Center
Antioch, California, United States
Active, not recruiting
Providence Saint Joseph Medical Center/disney Family Cancer Center
Burbank, California, United States
Suspended
Enloe Medical Center
Chico, California, United States
Active, not recruiting
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Joanne E. Mortimer
Recruiting
Epic Care-Dublin
Dublin, California, United States
Suspended
Bay Area Breast Surgeons Inc
Emeryville, California, United States
Suspended
Epic Care Partners in Cancer Care
Emeryville, California, United States
Suspended
Kaiser Permanente-Fremont
Fremont, California, United States
Active, not recruiting
Fresno Cancer Center
Fresno, California, United States
Active, not recruiting
Kaiser Permanente-Fresno
Fresno, California, United States
Active, not recruiting
Usc / Norris Comprehensive Cancer Center
Los Angeles, California, United States
Priya Jayachandran
Recruiting
Contra Costa Regional Medical Center
Martinez, California, United States
Lisa Bailey
Recruiting
City of Hope Mission Hills
Mission Hills, California, United States
Joanne E. Mortimer
Recruiting
Kaiser Permanente-Modesto
Modesto, California, United States
Active, not recruiting
City of Hope Newport Beach
Newport Beach, California, United States
Joanne E. Mortimer
Recruiting
Alta Bates Summit Medical Center - Summit Campus
Oakland, California, United States
Active, not recruiting
Bay Area Tumor Institute
Oakland, California, United States
Suspended
Kaiser Permanente Oakland-Broadway
Oakland, California, United States
Active, not recruiting

550 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Nov 2017
Primary completion: 15 Sept 2027
Completion: 15 Sept 2027
Last update posted: 8 Oct 2025
Registered enrollment: 491
Registry id: NCT03418961

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.