Clinical trialNCT03422003Active, not recruitingInterventional

Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma

SponsorDana-Farber Cancer InstituteEnrollment400Breast Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is a randomized trial of hypofractionation (short-course) radiation therapy versus conventional radiation therapy in women who have undergone mastectomy and immediate breast reconstruction. The investigators will assess cosmetic and reconstruction outcomes, lymphedema, cancer status, side effects, and oncologic outcomes.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Julia Wong, MD
Dana-Farber Cancer Institute
Study Chair
clinicaltrials.gov ↗
Rinaa Punglia, MD MPH
Dana-Farber Cancer Institute
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California, San Francisco
San Francisco, California, United States
Stanford University Medical Center
Stanford, California, United States
Vail Health
Edwards, Colorado, United States
Yale Cancer Center
New Haven, Connecticut, United States
Johns Hopkins Medicine
Washington D.C., District of Columbia, United States
Eastern Maine Medical Center
Brewer, Maine, United States
Maine Medical Center
Scarborough, Maine, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Dana Farber Cancer Institute
Boston, Massachusetts, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Massachusetts General Hospital/north Shore Center for Outpatient Care
Danvers, Massachusetts, United States
Dana-Farber/brigham and Women'S Cancer Center (df/bwcc) at Milford Regional Medical Center
Milford, Massachusetts, United States
Dana-Farber/brigham and Women'S Cancer Center in Clinical Affiliation With South Shore Hospital
South Weymouth, Massachusetts, United States
Lifespan/rhode Island Hospital
Providence, Rhode Island, United States
University of Washington
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Apr 2018
Primary completion: 31 Oct 2023
Completion: 1 Apr 2030
Last update posted: 1 Nov 2024
Registered enrollment: 400
Registry id: NCT03422003

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.