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Clinical trialNCT03423628RecruitingPhase 1Interventional

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

SponsorAstraZenecaEnrollment180Brain Neoplasms, MalignantLeptomeningeal Disease (LMD)Primary Glioblastoma MultiformeRecurrent Glioblastoma Multiforme
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Japan
  • Research Site

    Chūōku, Japan

    Completed
  • Research Site

    Hidaka-shi, Japan

    Active, not recruiting
  • Research Site

    Kyoto, Japan

    Active, not recruiting
United Kingdom
  • Research Site

    Cambridge, United Kingdom

    Active, not recruiting
  • Research Site

    Glasgow, United Kingdom

    Completed
  • Research Site

    Leeds, United Kingdom

    Recruiting
  • Research Site

    London, United Kingdom

    Withdrawn
United States
  • Research Site

    Boston, Massachusetts, United States

    Recruiting
  • Research Site

    Boston, Massachusetts, United States

    Recruiting
  • Research Site

    New York, New York, United States

    Recruiting
  • Research Site

    Pittsburgh, Pennsylvania, United States

    Recruiting
  • Research Site

    Richmond, Virginia, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Azd-1390
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
2 Apr 2018
Primary completion
16 Sept 2026
Completion
16 Sept 2026
Last update posted
22 Dec 2025
Registered enrollment
180
Registry id
NCT03423628

Cross-registrations

EU-CTR / CTIS (EudraCT)2017-002451-28

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.