Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS
Summary
The lay summary the sponsor registered on ClinicalTrials.gov.
Investigators
The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.
- Nikos Evangelou, MD, DPhil
University of Nottingham
Principal Investigator
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
30 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- University Hospitals Coventry and Warwickshire
Coventry, England, United Kingdom
- the Leeds Teaching Hospitals Nhs Trust, Leeds General Infirmary
Leeds, England, United Kingdom
- University Hospitals Leicester
Leicester, England, United Kingdom
- Imperial College Healthcare Nhs Trust, Charing Cross Hospital
London, England, United Kingdom
- University College London Hospitals Nhs Foundation Trust, University College Hospital
London, England, United Kingdom
- Salford Royal Nhs Foundation Trust, Salford Hospital
Manchester, England, United Kingdom
- Oxford University Hospitals Nhs Foundation Trust, John Radcliffe Hospital
Oxford, England, United Kingdom
- University Hospitals Plymouth Nhs Trust, Derriford Hospital
Plymouth, England, United Kingdom
- Sheffield Teaching Hospitals
Sheffield, England, United Kingdom
- University Hospitals of North Midlands
Stoke, England, United Kingdom
- Royal Infirmary of Edinburgh
Edinburgh, Scotland, United Kingdom
- Cardiff and Vale University Local Health Board, University Hospital of Wales
Cardiff, Wales, United Kingdom
- Aneurin Bevan Local Health Board Headquarters, Royal Gwent Hospital
Newport, Wales, United Kingdom
- Swansea Bay University Local Health Board, Morriston Hospital
Swansea, Wales, United Kingdom
- Nottingham University Hospitals Nhs Trust, Queens Medical Centre
Nottingham, United Kingdom
- University of Colorado-Anschutz Medical Campus
Aurora, Colorado, United States
- University of Minnesota
Minneapolis, Minnesota, United States
- Mayo Clinic
Rochester, Minnesota, United States
- Cleveland Clinic Lou Ruvo Center for Brain Health
Las Vegas, Nevada, United States
- University of Buffalo
Buffalo, New York, United States
- University Rochester Medical Center
Rochester, New York, United States
- University of Cincinnati
Cincinnati, Ohio, United States
- Cleveland Clinic
Cleveland, Ohio, United States
- Ohio Health
Columbus, Ohio, United States
- Ut-Austin
Austin, Texas, United States
- Baylor College of Medicine, Houston
Houston, Texas, United States
- Uthealth-Houston
Houston, Texas, United States
- University of Virginia
Charlottesville, Virginia, United States
- Virginia Commonwealth University
Richmond, Virginia, United States
- University of Wisconsin-Madison
Madison, Wisconsin, United States
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 3 Jan 2019
- Primary completion
- 30 Jul 2027
- Completion
- 30 Jul 2027
- Last update posted
- 28 Aug 2025
- Registered enrollment
- 800
- Registry id
- NCT03535298
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.