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Clinical trialNCT03541187CompletedPhase 2Interventional

Cockroach Immunotherapy in Children and Adolescents

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment82Persistent Asthma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Scientific evidence has shown that, over the past two decades, the combination of cockroach allergy and cockroach exposure is one of the most important factors contributing to the dramatic increase in asthma morbidity seen in inner city children with asthma. Therefore, a major goal of the Inner City Asthma Consortium (ICAC) is to evaluate the efficacy of cockroach immunotherapy in inner city asthma. The primary objective of the study is to determine if the response to nasal allergen challenge (NAC) will be changed with treatment with cockroach subcutaneous immunotherapy (SCIT) treatment.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Edward M. Zoratti, MD

    Henry Ford Health System: Division of Allergy and Immunology

    Study Chair
  • Robert Wood, MD

    Johns Hopkins Children's Center: Department of Allergy & Immunology

    Study Chair

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Children'S Hospital Colorado

    Aurora, Colorado, United States

  • Children'S National Medical Center - Impact Dc

    Washington D.C., District of Columbia, United States

  • Ann and Robert Lurie Children'S Hospital of Chicago

    Chicago, Illinois, United States

  • Johns Hopkins University

    Baltimore, Maryland, United States

  • Boston Medical Center

    Boston, Massachusetts, United States

  • Henry Ford Health System: Division of Allergy and Immunology

    Detroit, Michigan, United States

  • St. Louis Children'S Hospital: Allergy, Immunology and Pulmonary Medicine Program

    St Louis, Missouri, United States

  • Columbia University Medical Center

    New York, New York, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, United States

  • Cincinnati Children'S Hospital

    Cincinnati, Ohio, United States

  • University of Texas Southwestern Medical School

    Dallas, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

German cockroach allergenic extractPlacebo for German cockroach allergenic extract
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
16 Jul 2018
Primary completion
2 Jun 2022
Completion
3 Jun 2022
Last update posted
22 May 2023
Registered enrollment
82
Registry id
NCT03541187

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.