findmyKOL
Clinical trialNCT03570801Active, not recruitingInterventional

SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

SponsorLahey ClinicEnrollment662Degenerative SpondylolisthesisGrade 1 SpondylolisthesisLumbar Spinal StenosisLumbar Spondylolisthesis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of the project is to perform an RCT comparing patient satisfaction and outcome with or without the use of an expert panel. The purpose is also to create a registry to compare the effectiveness of decompression alone versus decompression with fusion for patients with degenerative grade I spondylolisthesis and symptomatic lumbar spinal stenosis. Primary analysis will focus on the patients' improvement from baseline patient-reported outcome questionnaires. In addition, the SLIP II registry aims to (i) develop an algorithm which could identify cases in which surgical experts are likely to recommend one treatment (i.e. \>80% of experts recommend one form of treatment) and (ii) develop a radiology-based machine learning algorithm that would prospectively classify patients as either 'stable' or 'unstable.' In addition to patient reported outcomes, step counts will be collected in order to determine the correlation of step count with patient-reported outcomes (ODI and EQ-5D) and the need for re-operation. This registry portion of the study aims to prospectively collect comparative data for these patients treated with either decompression alone or decompression with fusion.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

17 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • University Health Network - Toronto Western Hospital

    Toronto, Ontario, Canada

United States
  • Barrow Brain and Spine

    Scottsdale, Arizona, United States

  • University of California, San Fransisco

    San Francisco, California, United States

  • University of Miami

    Miami, Florida, United States

  • Carle Neurosciences Institute

    Urbana, Illinois, United States

  • Goodman Campbell Brain & Spine

    Carmel, Indiana, United States

  • Norton Leatherman Spine Center

    Louisville, Kentucky, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, United States

  • Lahey Hospital & Medical Center

    Burlington, Massachusetts, United States

  • University of Minnesota

    Minneapolis, Minnesota, United States

  • Mayo Clinic

    Rochester, Minnesota, United States

  • Columbia University

    New York, New York, United States

  • Hospital for Special Surgery

    New York, New York, United States

  • Cleveland Clinic Foundation

    Cleveland, Ohio, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, United States

  • University of Utah Hospital

    Salt Lake City, Utah, United States

  • University of Wisconsin

    Madison, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
17 Oct 2017
Primary completion
31 Dec 2028
Completion
31 Dec 2028
Last update posted
29 Sept 2025
Registered enrollment
662
Registry id
NCT03570801

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.