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Clinical trialNCT03598244Active, not recruitingPhase 1Interventional

Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

SponsorNational Cancer Institute (NCI)Enrollment41Recurrent Diffuse Intrinsic Pontine GliomaRecurrent Malignant GliomaRecurrent MedulloblastomaRecurrent Primary Central Nervous System NeoplasmRefractory Diffuse Intrinsic Pontine GliomaRefractory Malignant Glioma+2 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Hospital for Sick Children

    Toronto, Ontario, Canada

United States
  • Children'S Hospital Los Angeles

    Los Angeles, California, United States

  • Lucile Packard Children'S Hospital Stanford University

    Palo Alto, California, United States

  • Children'S Hospital Colorado

    Aurora, Colorado, United States

  • Children'S National Medical Center

    Washington D.C., District of Columbia, United States

  • Lurie Children'S Hospital-Chicago

    Chicago, Illinois, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

  • Nationwide Children'S Hospital

    Columbus, Ohio, United States

  • Children'S Hospital of Pittsburgh of Upmc

    Pittsburgh, Pennsylvania, United States

  • Saint Jude Children'S Research Hospital

    Memphis, Tennessee, United States

  • Texas Children'S Hospital

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
27 Nov 2018
Primary completion
14 Apr 2025
Completion
12 Sept 2026
Last update posted
23 Jun 2026
Registered enrollment
41
Registry id
NCT03598244

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.