Clinical trialNCT03606967RecruitingPhase 2Interventional

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

SponsorNational Cancer Institute (NCI)Enrollment70Anatomic Stage IV Breast Cancer AJCC v8Invasive Breast CarcinomaMetastatic Triple-Negative Breast Carcinoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

William E Gillanders
Yale University Cancer Center LAO
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

30 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Uc Irvine Health/chao Family Comprehensive Cancer Center
Orange, California, United States
Active, not recruiting
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Terminated
Uchealth University of Colorado Hospital
Aurora, Colorado, United States
Jennifer R. Diamond
Recruiting
Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut, United States
Active, not recruiting
Yale University
New Haven, Connecticut, United States
Active, not recruiting
Um Sylvester Comprehensive Cancer Center at Aventura
Aventura, Florida, United States
Alejandra T. Perez
Recruiting
Um Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, United States
Alejandra T. Perez
Recruiting
Um Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, United States
Alejandra T. Perez
Recruiting
Um Sylvester Comprehensive Cancer Center at Kendall
Miami, Florida, United States
Alejandra T. Perez
Recruiting
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States
Alejandra T. Perez
Recruiting
Um Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, United States
Alejandra T. Perez
Recruiting
Moffitt Cancer Center
Tampa, Florida, United States
Aixa E. Soyano
Recruiting
Moffitt Cancer Center - Mckinley Campus
Tampa, Florida, United States
Aixa E. Soyano
Recruiting
Moffitt Cancer Center-International Plaza
Tampa, Florida, United States
Aixa E. Soyano
Recruiting
Moffitt Cancer Center at Wesley Chapel
Wesley Chapel, Florida, United States
Aixa E. Soyano
Recruiting
Johns Hopkins University/sidney Kimmel Cancer Center
Baltimore, Maryland, United States
Cesar A. Santa-Maria
Recruiting
Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, Missouri, United States
William E. Gillanders
Recruiting
Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri, United States
William E. Gillanders
Recruiting
Siteman Cancer Center at Christian Hospital
St Louis, Missouri, United States
William E. Gillanders
Recruiting
Siteman Cancer Center-South County
St Louis, Missouri, United States
William E. Gillanders
Recruiting
Washington University School of Medicine
St Louis, Missouri, United States
William E. Gillanders
Recruiting
Dartmouth Hitchcock Medical Center/dartmouth Cancer Center
Lebanon, New Hampshire, United States
Suspended
Nyp/weill Cornell Medical Center
New York, New York, United States
Massimo Cristofanilli →
Recruiting
Wake Forest University at Clemmons
Clemmons, North Carolina, United States
Emily H. Douglas
Recruiting
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Emily H. Douglas
Recruiting
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States
Kai C. Johnson
Recruiting
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
Active, not recruiting
University of Pittsburgh Cancer Institute (upci)
Pittsburgh, Pennsylvania, United States
Julia Foldi
Recruiting
University of Texas Medical Branch
Galveston, Texas, United States
Avi B. Markowitz
Recruiting
Vcu Massey Comprehensive Cancer Center
Richmond, Virginia, United States
Masey M. Ross
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Carboplatin →Durvalumab →Gemcitabine →Paclitaxel →Personalized Synthetic Long Peptide VaccinePoly ICLCSacituzumab →Tremelimumab →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 13 Apr 2021
Primary completion: 30 Dec 2026
Completion: 30 Dec 2026
Last update posted: 12 Jun 2026
Registered enrollment: 70
Registry id: NCT03606967

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.