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Clinical trialNCT03618095TerminatedInterventional

REPRISE IV: LOTUS Edge Valve System in Intermediate Surgical Risk Subjects

SponsorBoston Scientific CorporationEnrollment382Aortic Valve Stenosis
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

50 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Monash Cardiovascular Research Centre

    Clayton, Victoria, Australia

United States
  • Huntsville Hospital

    Huntsville, Alabama, United States

  • Tucson Medical Center

    Tucson, Arizona, United States

  • Arkansas Heart Hospital

    Little Rock, Arkansas, United States

  • Mills-Peninsula Medical Center - Sutter Health

    Burlingame, California, United States

  • Kaiser Permanente Los Angeles Medical Center

    Los Angeles, California, United States

  • Usc Medical Center

    Los Angeles, California, United States

  • Saint Joseph Hospital

    Denver, Colorado, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, United States

  • Medstar Heart and Vascular Institute

    Washington D.C., District of Columbia, United States

  • Jfk Medical Center

    Atlantis, Florida, United States

  • North Florida Regional Medical Center

    Gainesville, Florida, United States

  • Adventhealth Orlando

    Orlando, Florida, United States

  • Piedmont Heart Institute

    Atlanta, Georgia, United States

  • Wellstar Research Institute

    Marietta, Georgia, United States

  • Northshore University Healthsystem

    Evanston, Illinois, United States

  • Indiana University Health - Methodist Hospital

    Indianapolis, Indiana, United States

  • Via Christi Hospital

    Wichita, Kansas, United States

  • Ochsner Medical Center

    New Orleans, Louisiana, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, United States

  • Charlton Memorial Hospital - Southcoast Health

    Fall River, Massachusetts, United States

  • Spectrum Health - Grand Rapids

    Grand Rapids, Michigan, United States

  • Cardiac & Vascular Research Center of Northern Michigan

    Petoskey, Michigan, United States

  • Beaumont Hospital

    Royal Oak, Michigan, United States

  • St. Cloud Hospital

    Saint Cloud, Minnesota, United States

  • Englewood Hospital

    Englewood, New Jersey, United States

  • Morristown Medical Center

    Morristown, New Jersey, United States

  • North Shore University Hospital

    Manhasset, New York, United States

  • Nyu Winthrop Hospital

    Mineola, New York, United States

  • Columbia University Medical Center/newyork Presbyterian Hospital

    New York, New York, United States

  • Nyu Langone Medical Center

    New York, New York, United States

  • Novant Health Heart & Vascular Institute - Charlotte

    Charlotte, North Carolina, United States

  • Unc Rex Hospital

    Raleigh, North Carolina, United States

  • the Lindner Center for Research and Education

    Cincinnati, Ohio, United States

  • Providence St. Vincent Medical Center

    Portland, Oregon, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Allegheny General Hospital

    Pittsburgh, Pennsylvania, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, United States

  • Greenville Memorial Hospital - Prisma Health

    Greenville, South Carolina, United States

  • Centennial Medical Center

    Nashville, Tennessee, United States

10 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
14 Jan 2019
Primary completion
30 Mar 2021
Completion
31 Mar 2021
Last update posted
27 Dec 2022
Registered enrollment
382
Registry id
NCT03618095

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.