Clinical trialNCT03674970CompletedPhase 1/PHASE2Interventional

Effects of Random Nicotine Delivery on Smoking Cessation

SponsorMilton S. Hershey Medical CenterEnrollment45Cigarette SmokingSmoking (Tobacco) AddictionSmoking Cessation

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The objective of this study is to determine whether treatment with random nicotine delivery via a nicotine film both before and after the target quit date will facilitate smoking cessation relative to treatment with steady state delivery or placebo. The investigators hypothesize that smoking cessation will be greater in subjects assigned to a random nicotine delivery regimen (as compared to those assigned to a steady state or placebo regimen). The nicotine film product is not part of the standard of care and is not available in non-investigational settings in the United States.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Christopher Sciamanna, MD
Penn State College of Medicine
Study Director
clinicaltrials.gov ↗
Jonathan Foulds, PhD
Penn State College of Medicine
Principal Investigator
clinicaltrials.gov ↗
Patricia S Grigson, PhD
Penn State College of Medicine
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Penn State Health Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Nicotine Film

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 12 Mar 2019
Primary completion: 25 Nov 2019
Completion: 25 Nov 2019
Last update posted: 22 Jan 2021
Registered enrollment: 45
Registry id: NCT03674970

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.