Clinical trialNCT03680040TerminatedObservational

RESILIENCE Trial: Evaluation of the Durability of Aortic Bioprostheses/Valves With RESILIA Tissue in Subjects Under 65

SponsorEdwards LifesciencesEnrollment110Aortic Valve Replacement

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The objective of this observational trial is to determine time to valve failure due to valve deterioration requiring re-intervention and collect/investigate early potential predictors of valve durability (e.g., calcification and hemodynamic deterioration) in RESILIA tissue valves.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Joseph Bavaria, MD
Organizational Affiliation: Hospital of the University of Pennsylvania
Principal Investigator
clinicaltrials.gov ↗
Lars Svensson, MD, PhD
The Cleveland Clinic
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Southern California
Los Angeles, California, United States
University of Florida - Shands Hospital
Gainesville, Florida, United States
University of Maryland, Baltimore
Baltimore, Maryland, United States
Columbia University Medical Center-Ny Presbyterian Hospital
New York, New York, United States
Weill Cornell - Nyc
New York, New York, United States
Cleveland Clinic Foundation
Cleveland, Ohio, United States
Pinnacle Health
Mechanicsburg, Pennsylvania, United States
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Baylor College of Medicine - St. Luke'S Hospital
Houston, Texas, United States
the Heart Hospital of Baylor Plano
Plano, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 5 Nov 2018
Primary completion: 13 Feb 2024
Completion: 13 Feb 2024
Last update posted: 9 May 2024
Registered enrollment: 110
Registry id: NCT03680040

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.