Clinical trialNCT03682991Active, not recruitingInterventional

Reversal of Atrial Substrate to Prevent Atrial

SponsorNova Scotia Health AuthorityEnrollment509Atrial Fibrillation

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A multi-center, randomized trial to examine the effect of aggressive risk factor control and arrhythmia trigger-based intervention on recurrence of atrial fibrillation.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Allan Skanes
London Health Sciences Centre
Study Director
clinicaltrials.gov ↗
Anthony Tang
London Health Sciences Centre
Study Director
clinicaltrials.gov ↗
Chris Blanchard
Nova Scotia Health
Study Director
clinicaltrials.gov ↗
David Birnie
University of Ottawa Heart Institution
Study Director
clinicaltrials.gov ↗
George Wells
University of Ottawa Heart Institution
Study Director
clinicaltrials.gov ↗
Isabelle vanGelder
University of Groningen
Study Director
clinicaltrials.gov ↗
Jeff Healey
Hamilton Health Sciences Centre
Study Director
clinicaltrials.gov ↗
Jennifer Reed
University of Ottawa Heart Institution
Study Director
clinicaltrials.gov ↗
John Sapp
Nova Scotia Health Authority
Study Director
clinicaltrials.gov ↗
Michiel Rienstra
University of Groningen
Study Director
clinicaltrials.gov ↗
Ratika Parkash
Nova Scotia Health Authority
Principal Investigator
clinicaltrials.gov ↗
Vidal Essebag
McGill University Hospital
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

17 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Foothills Hospital
Calgary, Alberta, Canada
Mazankowski Alberta Heart Institute
Edmonton, Alberta, Canada
Kelowna General Health
Kelowna, British Columbia, Canada
St. Paul'S Hospital
Vancouver, British Columbia, Canada
Saint John Regional Hospital
Saint John, New Brunswick, Canada
Qe Ii Health Sciences Centre
Halifax, Nova Scotia, Canada
Hamilton Health Sciences Center
Hamilton, Ontario, Canada
St. Mary'S General Hospital
Kitchener, Ontario, Canada
London Health Sciences Center
London, Ontario, Canada
Ottawa Heart Institute
Ottawa, Ontario, Canada
St. Michael'S Hospital
Toronto, Ontario, Canada
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Laval Hospital
Laval, Quebec, Canada
Mcgill University Health Centre
Montreal, Quebec, Canada
Montreal Heart Institute
Montreal, Quebec, Canada
Sacre Coeur Hospital
Montreal, Quebec, Canada
Regina General Hospital
Regina, Saskatchewan, Canada

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Jul 2019
Primary completion: 15 Sept 2027
Completion: 31 Dec 2027
Last update posted: 17 Feb 2026
Registered enrollment: 509
Registry id: NCT03682991

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.