Clinical trialNCT03701581RecruitingPhase 2/PHASE3Interventional

4-aminopyridine Treatment for Nerve Injury

SponsorJohn ElfarEnrollment70Nerve InjuryProstate Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the role of 4-aminopyridine (4-AP) on the course of recovery after peripheral nerve traction and/or crush injury. This study aims to test the hypothesis that 4-aminopyridine speeds the often slow and unpredictable recovery after peripheral nerve traction and/or crush injuries.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

John Elfar, MD
University of Arizona
Study Chair
clinicaltrials.gov ↗
Rashid Sayyid, MD
University of Arizona
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Arizona
Tucson, Arizona, United States
Benjamin Lee, MDJohn Elfar, MDJuan Chipollini, MDRashid Sayyid, MD
Recruiting
University of Rochester
Rochester, New York, United States
Terminated

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Dalfampridine →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 5 Jun 2021
Primary completion: 31 Jul 2027
Completion: 31 Dec 2028
Last update posted: 17 Dec 2025
Registered enrollment: 70
Registry id: NCT03701581

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.