A Long Term Study to Find Out if Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease
Summary
The lay summary the sponsor registered on ClinicalTrials.gov.
Investigators
The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.
- William Byra, MD
Actelion
Study Director
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
44 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- Instituto de Investigaciones Clinicas Mar del Plata
Mar del Plata, Argentina
- Medizinische Universitaet Wien
Vienna, Austria
- Maestri E Kormann Consultoria Médico- Científica Ltda
Blumenau, Brazil
- Instituto Do Coracao de Marília
Marília, Brazil
- Diagnostic Consulting Center I Sliven
Sliven, Bulgaria
- Medical Centre Synexus
Sofia, Bulgaria
- Bispebjerg Og Frederiksberg Hospital
Copenhagen, Denmark
- Chu de Grenoble Hopital Albert Michallon
Grenoble, France
- Hopital de Bicetre
Le Kremlin-Bicêtre, France
- Chu Rouen Hopital Charles Nicolle
Rouen, France
- Universitätsklinikum Carl Gustav Carus Medizinische Klinik Und Poliklinik 1-Pneumologie
Dresden, Germany
- Universitaetsklinikum Giessen
Giessen, Germany
- Universitaetsklinikum Schleswig Holstein Campus Kiel
Kiel, Germany
- Semmelweis Egyetem Varosmajor Sziv Es Ergyogyaszati Klinika
Budapest, Hungary
- Barzilai Medical Center
Ashkelon, Israel
- Hillel Yaffe Medical Center
Hadera, Israel
- Bnai Zion Medical Center
Haifa, Israel
- Galilee Medical Center
Nahariya, Israel
- Rabin Medical Center Beilinson Campus
Petah Tikva, Israel
- Kaplan Medical Center
Rehovot, Israel
- Krakowski Szpital Specjalityczny Im Jana Pawla Ii Oddzial Kliniczny Chorob Serca I Naczyn
Krakow, Poland
- Wojewodzki Szpital Specjalistyczny Im Stefana Kardynala Wyszynskiego Spzoz
Lublin, Poland
- 4 Wojskowy Szpital Kliniczny Z Poliklinika Sp Zoz
Wroclaw, Poland
- Cardiomed
Craiova, Romania
- Sal Med Pitesti
Piteşti, Romania
- Cmi Dr Podoleanu Cristian
Târgu Mureş, Romania
- Federal State Budget Scientific Institution
Kemerovo, Russia
- Moscow City Clinical Hospital No.51
Moscow, Russia
- Federal State Budgetary Institution
Saint Petersburg, Russia
- Ekaterinburg City Clinical Hospital #14
Yekaterinburg, Russia
- Sahlgrenska Universitetsjukhuset
Gothenburg, Sweden
- Royal Free Hospital
London, United Kingdom
- Sheffield Teaching Hospitals Nhs Foundation Trust Royal Hallamshire Hospital
Sheffield, United Kingdom
- South Denver Cardiology Associates Pc
Littleton, Colorado, United States
- Northwestern University Feinberg School of Medicine
Chicago, Illinois, United States
- University of Iowa - Hospitals & Clinics
Iowa City, Iowa, United States
- University of Maryland
Baltimore, Maryland, United States
- Massachusetts General Hospital
Boston, Massachusetts, United States
- Washington University School of Medicine
St Louis, Missouri, United States
- Allegheny
Pittsburgh, Pennsylvania, United States
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 7 Dec 2018
- Primary completion
- 12 Oct 2021
- Completion
- 12 Oct 2021
- Last update posted
- 4 Feb 2025
- Registered enrollment
- 91
- Registry id
- NCT03714815
Cross-registrations
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.