Clinical trialNCT03734237Active, not recruitingPhase 4Interventional

A Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD

SponsorHenry M. Jackson Foundation for the Advancement of Military MedicineEnrollment15,448InfluenzaInfluenza VaccinesInfluenza-like Illness

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A total of 18,000 eligible subjects (or 6,000 subject distributed evenly between the 3 study arms) will be enrolled. Eligible subjects will be randomized in 1:1:1 (cell-culture-based vaccine, the recombinant vaccine, or the egg-based vaccine) over four influenza seasons (2018-2019, 2019-2020, 2020-2021, and 2021-2022).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Rhonda Colombo, MD
Infectious Diseases Clinical Research Program
Study Director
clinicaltrials.gov ↗
Timothy Burgess, MD
Uniformed Services University of the Health Sciences
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Naval Medical Center San Diego
San Diego, California, United States
United States Naval Academy
Annapolis, Maryland, United States
Usu
Bethesda, Maryland, United States
Walter Reed National Military Medical Center
Bethesda, Maryland, United States
Womack Army Medical Center
Fort Bragg, North Carolina, United States
Brooke Army Medical Center
Fort Sam Houston, Texas, United States
Lackland Airforce Base
San Antonio, Texas, United States
Naval Medical Center Portsmouth
Portsmouth, Virginia, United States
Madigan Army Medical Center
Tacoma, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Cell-culture based influenza vaccinesEgg based influenza vaccinesRecombinant influenza vaccines

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 6 Nov 2018
Primary completion: 7 Jul 2022
Completion: 30 Jun 2026
Last update posted: 2 Apr 2026
Registered enrollment: 15,448
Registry id: NCT03734237

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.