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Clinical trialNCT03734588CompletedPhase 1/PHASE2Interventional

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

SponsorSpark Therapeutics, Inc.Enrollment4Adeno-Associated Virus (AAV)Blood Coagulation DisorderBlood Coagulation Disorders, InheritedCoagulation Protein DisordersFactor VIII (FVIII)Factor VIII (FVIII) Deficiency+11 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Orthopaedic Institute for Children

    Los Angeles, California, United States

  • Illinois Bleeding and Clotting Disorders Institute

    Peoria, Illinois, United States

  • University of Michigan

    Ann Arbor, Michigan, United States

  • Mississippi Center for Advanced Medicine

    Madison, Mississippi, United States

  • Weill Cornell Medicine

    New York, New York, United States

  • Oregon Health & Science University

    Portland, Oregon, United States

  • Penn State Health

    Hershey, Pennsylvania, United States

  • Children'S Hospital of Philadelphia

    Philadelphia, Pennsylvania, United States

  • Jefferson University Hospitals

    Philadelphia, Pennsylvania, United States

  • Hemophilia Center of Western Pennsylvania

    Pittsburgh, Pennsylvania, United States

  • Virginia Commonwealth University School of Medicine

    Richmond, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Jan 2019
Primary completion
14 Oct 2020
Completion
19 Jan 2023
Last update posted
23 Feb 2024
Registered enrollment
4
Registry id
NCT03734588

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.