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Clinical trialNCT03739996CompletedPhase 2Interventional

Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment75HIV Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study was to assess the safety, tolerability, antiviral activity, and pharmacokinetics of long-acting cabotegravir (CAB LA) plus the broadly neutralizing monoclonal antibody VRC-HIVMAB075-00-AB (VRC07-523LS), in adults living with HIV-1 with suppressed plasma viremia.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

18 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico
  • Puerto Rico Aids Clinical Trials Unit Crs

    San Juan, Puerto Rico

United States
  • Alabama Crs

    Birmingham, Alabama, United States

  • Ucsd Antiviral Research Center Crs

    San Diego, California, United States

  • Ucsf Hiv/aids Crs

    San Francisco, California, United States

  • University of Colorado Hospital Crs

    Aurora, Colorado, United States

  • Northwestern University Crs

    Chicago, Illinois, United States

  • Johns Hopkins University Crs

    Baltimore, Maryland, United States

  • Washington University Therapeutics (wt) Crs

    St Louis, Missouri, United States

  • New Jersey Medical School Clinical Research Center Crs

    Newark, New Jersey, United States

  • Columbia P&s Crs

    New York, New York, United States

  • Weill Cornell Chelsea Crs

    New York, New York, United States

  • Weill Cornell Uptown Crs

    New York, New York, United States

  • University of Rochester Adult Hiv Therapeutic Strategies Network Crs

    Rochester, New York, United States

  • Chapel Hill Crs

    Chapel Hill, North Carolina, United States

  • Cincinnati Clinical Research Site

    Cincinnati, Ohio, United States

  • Ohio State University Crs

    Columbus, Ohio, United States

  • Penn Therapeutics, Crs

    Philadelphia, Pennsylvania, United States

  • University of Washington Aids Crs

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Long-Acting Injectable CabotegravirNucleoside Reverse Transcriptase InhibitorsCabotegravir →Standard of Care ARTVRC07-523LS
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Dec 2019
Primary completion
29 Apr 2024
Completion
29 Apr 2024
Last update posted
23 May 2025
Registered enrollment
75
Registry id
NCT03739996

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.