findmyKOL
Clinical trialNCT03742414Active, not recruitingPhase 2Interventional

Seal, Stopping Eczema and Allergy Study

SponsorKari Nadeau, MD, PhDEnrollment398Atopic DermatitisAtopic Dermatitis EczemaEczemaEczema, Infantile
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a randomized, controlled trial designed for children who are have already developed atopic dermatitis (AD or eczema) by 12 weeks of age. The aim is to compare the effect of proactive sequential skin care, including the twice-daily use of a tri-lipid skin barrier cream (Epiceram) and proactive use of fluticasone propionate cream, against reactive AD therapy, to reduce the occurrence and severity of AD in early infancy and thereby prevent food allergy (FA).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United Kingdom
  • • King'S College London and Guy'S and St. Thomas' Nhs Foundation Trust, Uk

    London, London, United Kingdom

United States
  • Sean N. Parker Center for Allergy & Asthma Research at Stanford University

    Palo Alto, California, United States

  • Division of Pediatric Allergy and Clinical Immunology, National Jewish Health

    Denver, Colorado, United States

  • University of Chicago

    Chicago, Illinois, United States

  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Jun 2021
Primary completion
31 May 2028
Completion
30 Jun 2028
Last update posted
27 Feb 2026
Registered enrollment
398
Registry id
NCT03742414
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.