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Clinical trialNCT03786926TerminatedPhase 1Interventional

Trial to Evaluate the Safety and Pharmacokinetics of HMPL-689 in Patients With Lymphomas

SponsorHutchmedEnrollment53Lymphoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

An open-label, dose escalation and expansion clinical trial to evaluate the safety, tolerability and PK of HMPL-689 in patients with relapsed or refractory lymphomas
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

27 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Finland
  • Helsingin Yliopistollinen Keskussairaala

    Helsinki, Finland

  • Tampereen Yliopistollinen Sairaala

    Tampere, Finland

France
  • Hopital Henri Mondor

    Créteil, Val De Marne, France

  • Chu de Nantes - Hotel Dieu

    Nantes, France

  • Chu de Bordeaux - Hôpital Haut-Lévêque

    Pessac, France

Italy
  • Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi Irccs

    Bologna, Italy

  • Ospedale San Raffaele

    Milan, Italy

Poland
  • Ko-Med Centra Kliniczne

    Biała Podlaska, Poland

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, Poland

  • Bioresearch Group Sp. Z. O. O.

    Krakow, Poland

  • Nasz Lekarz Osrodek Badan Klinicznych

    Torun, Poland

  • Uniwersytecki Szpital Kliniczny Im. Jana Mikulicza Radeckiego

    Wroclaw, Poland

Spain
  • Ico Badalona - Hospital Universitari Germans Trias I Pujol

    Barcelona, Spain

  • Ico L'Hospitalet - Hospital Duran I Reynals

    Barcelona, Spain

  • Fundacion Jimenez Diaz

    Madrid, Spain

  • Hospital Universitario Virgen Macarena

    Seville, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, Spain

United States
  • Innovative Clinical Research Institute

    Anaheim, California, United States

  • Pacific Cancer Medical Center

    Anaheim, California, United States

  • Ventura County Hematology-Oncology Specialists

    Oxnard, California, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, United States

  • Clinical Research Alliance, Inc

    Westbury, New York, United States

  • Levine Cancer Institute- Atrium Health

    Charlotte, North Carolina, United States

  • Baylor Scott and White Research Institute

    Dallas, Texas, United States

  • Renovatio Clinical

    Houston, Texas, United States

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas, United States

  • Medical Oncology Associates, P.S.

    Spokane, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

HMPL-689
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
26 Aug 2019
Primary completion
26 Jun 2024
Completion
26 Jun 2024
Last update posted
26 Jun 2025
Registered enrollment
53
Registry id
NCT03786926
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.