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Clinical trialNCT03805841TerminatedPhase 2Interventional

Study of Tarloxotinib in Pts With NSCLC (EGFR Exon 20 Insertion, HER2-activating Mutations) & Other Solid Tumors With NRG1/ERBB Gene Fusions

SponsorRain Oncology IncEnrollment41EGFR Exon 20 Insertion MutationERBB FusionHER2-activating MutationNRG1 FusionNSCLC Stage IIIBNSCLC, Recurrent+2 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Open-label, Phase 2, single treatment arm, 3 cohorts

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Rain-701 Study Site

    Toronto, Ontario, Canada

Hong Kong
  • Rain-701 Study Site

    Hong Kong, Hong Kong

  • Hong Kong United Oncology Center

    Kowloon, Hong Kong

United States
  • Rain-701 Study Site

    Irvine, California, United States

  • Pacific Shores Medical Group

    Long Beach, California, United States

  • University of California San Francisco, Helen Diller Cancer Center

    San Francisco, California, United States

  • Rain-701 Study Site

    Aurora, Colorado, United States

  • Georgetown University Medical Center

    Washington D.C., District of Columbia, United States

  • Comprehensive Care and Research Center, Atlanta

    Newnan, Georgia, United States

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, United States

  • Henry Ford Cancer Institute

    Detroit, Michigan, United States

  • Providence Cancer Institute

    Portland, Oregon, United States

  • Rain-701 Study Site

    Pittsburgh, Pennsylvania, United States

  • Rain-701 Study Site

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Tarloxotinib bromide
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
13 Mar 2019
Primary completion
9 Apr 2021
Completion
23 Apr 2021
Last update posted
28 Jun 2023
Registered enrollment
41
Registry id
NCT03805841

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.