Clinical trialNCT03818724UnknownObservational

Treatment Success With the CoolLoop Cryoablation System

Sponsorafreeze GmbHEnrollment540Arrhythmias, CardiacAtrial FibrillationCardiovascular DiseasesHeart DiseasesParoxysmal Atrial FibrillationPersistent Atrial Fibrillation

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This clinical study evaluates the safety and efficacy of the treatment with the CoolLoop® cryoablation System (sclerotherapy of muscle tissue of the heart by freezing) in patients with atrial fibrillation (permanent atrial fibrillation excepted) over a follow-up period of 36 months. A further aim of this study is to evaluate the average duration of procedure and fluoroscopy times.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Andreas Kaiser, PhD
afreeze GmbH
Study Director
clinicaltrials.gov ↗
Florian Hintringer, MD
Medical University Innsbruck
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Austria

Medical University Innsbruck
Innsbruck, Tirol/Austria, Austria
Recruiting

Germany

Marienhaus Klinikum St. Elisabeth Neuwied
Neuwied, Germany/Rheinland-Pfalz, Germany
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 17 Jan 2019
Primary completion: 31 Jan 2025
Completion: 31 Jan 2025
Last update posted: 21 Jul 2022
Registered enrollment: 540
Registry id: NCT03818724

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.