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Clinical trialNCT03829566WithdrawnPhase 2/PHASE3Interventional

Autologous Transplant To End NMO Spectrum Disorder

SponsorNorthwestern UniversityEnrollment0Devic's DiseaseNMO Spectrum DisorderNeuromyelitis Optica
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is designed to treat your disease with an autologous stem cell transplant using a regimen of immune suppressant drugs and chemotherapy to reset your immune system and to determine if your disease will go into long-term remission.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Northwestern University

    Chicago, Illinois, United States

  • Northwestern University, Feinberg School of Medicine

    Chicago, Illinois, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Autologous Stem CellsCyclophosphamide →G-CSF →IVIG →Mesna →Methylprednisolone →Rituximab →Lymphocyte immune globulin, anti-thymocyte globulin →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Nov 2019
Primary completion
31 Jan 2025
Completion
28 Nov 2025
Last update posted
20 Nov 2019
Registered enrollment
0
Registry id
NCT03829566
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.