Clinical trialNCT03858205RecruitingInterventional

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

SponsorUniversity of Southern CaliforniaEnrollment100Bone PainMetastatic Malignant Neoplasm in the BonePlasma Cell Myeloma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase II trial studies how well low-dose radiotherapy works in treating bone pain in patients with multiple myeloma that has spread to the bone. Radiation therapy uses high energy x-rays, gamma rays, neutrons, protons, or other sources to kill tumor cells and shrink tumors. Low-dose radiotherapy may be more convenient for patients and their families, may not interfere as much with the timing of chemotherapy, and may have less chance for short term or long-term side effects from the radiation.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Adam Garsa, MD
University of Southern California
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

City of Hope
Duarte, California, United States
Savita V Dandapani, MD
Recruiting
Cedars Sinai Medical Center
Los Angeles, California, United States
Leslie Ballas, MD
Recruiting
Los Angeles General Medical Center
Los Angeles, California, United States
Adam Garsa, MD
Recruiting
Usc / Norris Comprehensive Cancer Center
Los Angeles, California, United States
Adam Garsa, MD
Recruiting
Emory University Hospital/winship Cancer Institute
Atlanta, Georgia, United States
Mohammad K. Khan
Recruiting
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Andrea K. Ng
Recruiting
University of Minnesota - Masonic Cancer Center
Minneapolis, Minnesota, United States
Stephanie Terezakis, MD
Recruiting
Icahn School of Medicine at Mount Sinai
New York, New York, United States
Richard L. Bakst
Recruiting
University of Pennsylvania/abramson Cancer Center
Philadelphia, Pennsylvania, United States
John Plastaras, MD, PhD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 11 Mar 2019
Primary completion: 31 Dec 2026
Completion: 11 Mar 2027
Last update posted: 5 Jun 2026
Registered enrollment: 100
Registry id: NCT03858205

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.