Clinical trialNCT03888378CompletedPhase 2Interventional

Study to Evaluate the Safety and Efficacy of Minocycline Ointment in Subjects With Inflamed Meibomian Gland Dysfunction

SponsorHovione Scientia LimitedEnrollment270MGD-Meibomian Gland DysfunctionMeibomian Gland Dysfunction

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the efficacy and safety of two strengths of HY02 Ointment versus Vehicle administered twice daily for twelve weeks in subjects with a diagnosis of Inflamed Meibomian Gland Dysfunction.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

George Magrath, MD
Hovione Scientia Limited
Study Director
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

20 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Clinical Site - 4
Azusa, California, United States
Clinical Site - 16
Huntington Beach, California, United States
Clinical Site - 12
Inglewood, California, United States
Clinical Site - 13
Mission Hills, California, United States
Clinical Site 10
Rancho Cordova, California, United States
Clinical Site - 15
Jacksonville, Florida, United States
Clinical Site - 18
Largo, Florida, United States
Clinical Site - 6
Indianapolis, Indiana, United States
Clinical Site - 20
New Albany, Indiana, United States
Clinical Site - 19
Kansas City, Missouri, United States
Clinical Site - 3
St Louis, Missouri, United States
Clinical Site - 9
St Louis, Missouri, United States
Clinical Site - 7
Las Vegas, Nevada, United States
Clinical Site - 5
Asheville, North Carolina, United States
Clinical Site - 11
Mason, Ohio, United States
Clinical Site - 2
Memphis, Tennessee, United States
Clinical Site - 14
Cedar Park, Texas, United States
Clinical Site - 1
El Paso, Texas, United States
Clinical Site - 8
League City, Texas, United States
Clinical Site - 17
Norfolk, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

0.3% Topical Minocycline Ointment1% Topical Minocycline Ointment

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 2 Apr 2019
Primary completion: 18 Sept 2020
Completion: 1 Feb 2021
Last update posted: 5 Mar 2021
Registered enrollment: 270
Registry id: NCT03888378

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.